Results 141 to 150 of about 174,626,138 (254)

Using pde model and system dynamics model for describing multi-operation production lines [PDF]

open access: yes
: Two classes of models for describing production flow lines are analyzed. The use of models of these classes for the design of highly efficient control systems of production lines, the technological route of which consists of a large number of
D. Yemelianova   +3 more
core  

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source

Phloroglucinol inhibits human ureteral contractions via activation of cAMP‐PKA pathway

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Phloroglucinol is used to treat renal colic, especially when non‐steroidal anti‐inflammatory drugs are contraindicated. This study aimed to clarify its mechanism by examining effects on human ureteral contractility and underlying signalling pathways. Experimental Approach Urinary levels of neurokinin A (NKA), substance P
Hanwen Liu   +12 more
wiley   +1 more source

A Cathepsin-Triggered Size-Shrinkable Nanoparticle Enhances Fibrous Cap Penetration to Relieve Atherosclerosis. [PDF]

open access: yesAdv Healthc Mater
Liang X   +10 more
europepmc   +1 more source

Computing Skinning Weights via Convex Duality

open access: yesComputer Graphics Forum, EarlyView.
We present an alternate optimization method to compute bounded biharmonic skinning weights. Our method relies on a dual formulation, which can be optimized with a nonnegative linear least squares setup. Abstract We study the problem of optimising for skinning weights through the lens of convex duality.
J. Solomon, O. Stein
wiley   +1 more source

zwicker-group/py-pde: 0.36.0

open access: yes
<p>This version contains a larger reorganization of the grid classes, where we now separated the calculations concerning coordinate systems in separate classes. This will make code cleaner in the longterm and allow us to support additional features
Diego Volpatto   +7 more
core   +1 more source

SDFs from Unoriented Point Clouds using Neural Variational Heat Distances

open access: yesComputer Graphics Forum, EarlyView.
We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from unoriented point clouds. We first compute a small time step of heat flow (middle) and then use its gradient directions to solve for a neural SDF (right). Abstract We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from ...
Samuel Weidemaier   +5 more
wiley   +1 more source

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