Results 91 to 100 of about 225,423 (289)
ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger +15 more
wiley +1 more source
Partial Differential Equations for 3D Data Compression and Reconstruction [PDF]
This paper describes a PDE-based method for 3D reconstruction of surface patches. The PDE method is exploited using data obtained from standard 3D scanners.
Osman, Abdusslam +2 more
core
Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial
ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad +9 more
wiley +1 more source
Adaptive Uncertainty-Penalized Model Selection for Data-Driven PDE Discovery
IEEE AccessWe propose a new parameter-adaptive uncertainty-penalized Bayesian information criterion (UBIC) to discover the stable governing partial differential equation (PDE) composed of a few important terms.
Pongpisit Thanasutives +3 more
doaj +1 more source
Asymmetry in crystal facet dynamics of homoepitaxy by a continuum model
, 2017 In the absence of external material deposition, crystal surfaces usually relax to become flat by decreasing their free energy. We study an asymmetry in the relaxation of macroscopic plateaus, facets, of a periodic surface corrugation in 1+1 dimensions ...
Liu, Jian-Guo +3 more
core +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Preparation and Characterization of 5′-Phosphodiesterase from Barley Malt Rootlets
Natural Product Communications, 2010 Two 5′- phosphodiesterases (5′-PDE-a and 5′-PDE-b) were isolated from barley malt rootlets, and further purified by gel filtration on Sephadex G-25 and Sephadex G-75.
Jie Hua, Ke-long Huang
doaj +1 more source
Respiratory Research, 2004 Background The anti-inflammatory effects of the selective phosphodiesterase (PDE) inhibitors cilostazol (PDE 3), RO 20-1724 (PDE 4) and sildenafil (PDE 5) were examined in a murine model of allergic asthma.
Galbraith Deirdre +6 more
doaj +1 more source
Energy Science &Engineering, EarlyView.A numerical model of variable‐speed pumped storage unit (VSPSU) with full‐size converter (FSC) under fast speed control strategy is established. Additionally, the correctness of the model was validated by comparing with SIMSEN simulation results and text prototype data from NARI.
Weijia Yang +5 more
wiley +1 more source