Results 81 to 90 of about 33,386 (268)
Preparation and Characterization of 5′-Phosphodiesterase from Barley Malt Rootlets
Two 5′- phosphodiesterases (5′-PDE-a and 5′-PDE-b) were isolated from barley malt rootlets, and further purified by gel filtration on Sephadex G-25 and Sephadex G-75.
Jie Hua, Ke-long Huang
doaj +1 more source
Background The anti-inflammatory effects of the selective phosphodiesterase (PDE) inhibitors cilostazol (PDE 3), RO 20-1724 (PDE 4) and sildenafil (PDE 5) were examined in a murine model of allergic asthma.
Galbraith Deirdre +6 more
doaj +1 more source
Numerical PDE solvers outperform neural PDE solvers
We present DeepFDM, a differentiable finite-difference framework for learning spatially varying coefficients in time-dependent partial differential equations (PDEs). By embedding a classical forward-Euler discretization into a convolutional architecture, DeepFDM enforces stability and first-order convergence via CFL-compliant coefficient ...
Patrick Chatain +3 more
openaire +2 more sources
PDE-PRESERVING PROPERTIES [PDF]
A continuous linear operator \(T\) on the space of entire functions in \(d\) variables is called PDE-preserving for a given set \(\mathbb{P}\subseteq\mathbb{C}[\xi_1,\ldots,\xi_d]\) of polynomials if \(T\ker P(D)\subseteq P(D)\) for all \(P\in\mathbb P\), where \(P(D)\) is the differential operator obtained by replacing each variable \(\xi_j\) by ...
openaire +1 more source
Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad +9 more
wiley +1 more source
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley +1 more source
Phosphodiesterase type-5 (PDE-5) inhibitors are approved as the first line of therapy for the treatment of erectile dysfunction. However, different studies have been performed to study the use of these agents in other areas of urology.
Mehmet UMUL, Tekin Ahmet SEREL
doaj +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
This paper is a contribution to the Floquet ideas applied for multitime overdetermined linear first order PDE dynamical systems with multi- periodic coefficients.
Constantin Udrişte
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