Results 71 to 80 of about 116,861 (304)

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

Advanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia, Constantine Vogiatzis, Alejandra Planells‐Devesa, Emre Dikici, Caroline Vieira Maluf, Vasudev Vivekanand Nayak, Paulo G. Coelho, Lukasz Witek, Alicia Bilbao, Daniel Bilbao, Prasoon Mohan, Sapna Deo, Sylvia Daunert   +12 more
wiley   +1 more source

Consistent boundary conditions for PDE filter regularization in topology optimization

Structural And Multidisciplinary Optimization, 2020
Design variables in density-based topology optimization are typically regularized using filtering techniques. In many cases, such as stress optimization, where details at the boundaries are crucially important, the filtering in the vicinity of the design
M. Wallin, Niklas Ivarsson, O. Amir, D. Tortorelli   +3 more
semanticscholar   +1 more source

LE-PDE++: Mamba for accelerating PDEs Simulations

CoRR
Partial Differential Equations are foundational in modeling science and natural systems such as fluid dynamics and weather forecasting. The Latent Evolution of PDEs method is designed to address the computational intensity of classical and deep learning-based PDE solvers by proposing a scalable and efficient alternative.
Aoming Liang, Zhaoyang Mu, Qi liu, Ruipeng Li, Mingming Ge, Dixia Fan   +5 more
openaire   +2 more sources

Topology and Material Optimization in Ultra‐Soft Magneto‐Active Structures: Making Advantage of Residual Anisotropies

Advanced Materials, EarlyView.
Residual magnetization induces pronounced mechanical anisotropy in ultra‐soft magnetorheological elastomers, shaping deformation and actuation even without external magnetic fields. This study introduces a computational‐experimental framework integrating magneto‐mechanical coupling into topology optimization for designing soft magnetic actuators with ...
Carlos Perez‐Garcia, Rogelio Ortigosa, Jesús Martínez‐Frutos, Daniel Garcia‐Gonzalez   +3 more
wiley   +1 more source

Measuring cAMP Specific Phosphodiesterase Activity: A Two-step Radioassay

Bio-Protocol, 2020
Cyclic nucleotide degrading phosphodiesterase (PDE) enzymes are crucial to the fine tuning of cAMP signaling responses, playing a pivotal role in regulating the temporal and spatial characteristics of discrete cAMP nanodomains and hence the activity of ...
Connor Blair, Jiayue Ling, George Baillie   +2 more
doaj   +1 more source

Noise-aware physics-informed machine learning for robust PDE discovery

Machine Learning: Science and Technology, 2023
This work is concerned with discovering the governing partial differential equation (PDE) of a physical system. Existing methods have demonstrated the PDE identification from finite observations but failed to maintain satisfying results against noisy ...
Pongpisit Thanasutives, Takashi Morita, Masayuki Numao, Ken-ichi Fukui   +3 more
doaj   +1 more source

Uma análise do desempenho do método evolução diferencial na resolução do problema de despacho econômico com ponto de carregamento de válvula

Intermaths, 2021
Um dos problemas encontrados na área de Engenharia Elétrica é o problema de despacho econômico (PDE), que visa reduzir o custo total da energia calculando a geração de cada unidade vinculada à rede.
João Vitor Dias, Edméa Cássia Baptista, Edilaine Martins Soler   +2 more
doaj   +1 more source

Benchmarking Coaxial and Angular Optical Emission Spectroscopy With Recommendations for Reliable Compositional In Situ Monitoring During Laser Powder Bed Fusion

Advanced Materials Technologies, EarlyView.
ABSTRACT Real‐time insight into local chemistry is critical for reliable part quality in additive manufacturing, especially laser powder bed fusion (PBF‑LB/M), where rapid thermal cycles and localized evaporation can undermine part performance. Optical emission spectroscopy (OES) offers non‑intrusive, in situ plume monitoring, but detection geometry ...
Philipp Gabriel, Bastian Jülich, Anna Rosa Ziefuss, Florian Eibl, Stephan Barcikowski   +4 more
wiley   +1 more source

Reconfigurable application-specific photonic integrated circuit for solving partial differential equations

Nanophotonics
Solving mathematical equations faster and more efficiently has been a Holy Grail for centuries for scientists and engineers across all disciplines. While electronic digital circuits have revolutionized equation solving in recent decades, it has become ...
Ye Jiachi, Shen Chen, Peserico Nicola, Meng Jiawei, Ma Xiaoxuan, Nouri Behrouz Movahhed, Popescu Cosmin-Constantin, Hu Juejun, Kang Haoyan, Wang Hao, El-Ghazawi Tarek, Dalir Hamed, Sorger Volker J.   +12 more
doaj   +1 more source

Partial Differential Equation-Constrained Diffeomorphic Registration from Sum of Squared Differences to Normalized Cross-Correlation, Normalized Gradient Fields, and Mutual Information: A Unifying Framework

Sensors, 2022
This work proposes a unifying framework for extending PDE-constrained Large Deformation Diffeomorphic Metric Mapping (PDE-LDDMM) with the sum of squared differences (SSD) to PDE-LDDMM with different image similarity metrics.
Monica Hernandez, Ubaldo Ramon-Julvez, Daniel Sierra-Tome   +2 more
doaj   +1 more source