Results 51 to 60 of about 216,553 (331)
PDI Family Members as Guides for Client Folding and Assembly
International Journal of Molecular Sciences, 2020 Complicated and sophisticated protein homeostasis (proteostasis) networks in the endoplasmic reticulum (ER), comprising disulfide catalysts, molecular chaperones, and their regulators, help to maintain cell viability.
Shingo Kanemura +3 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Symurban Nanocrystals for Advanced Anti-Pollution Skincare [PDF]
, 2020 Several of most common dermatoses worldwide, e.g., psoriasis and atopic dermatitis, are worsened in their clinical picture when the skin is regularly exposed to an increased air pollution level, e.g., particulate matter.
Köpke, Daniel, Pyo, Sung Min
core +1 more source
Advanced Functional Materials, EarlyView.For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin +7 more
wiley +1 more source
Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy
Cancer Medicine, 2021 The protein disulphide isomerase (PDI) gene family is a large, diverse group of enzymes recognised for their roles in disulphide bond formation within the endoplasmic reticulum (ER).
Lauren E. Powell, Paul A. Foster
doaj +1 more source
Molecules, 2023 Perylenediimide (PDI) compounds are widely used as the active units of thin-film organic lasers. Lately, PDIs bearing two sterically hindering diphenylphenoxy groups at the 1,7-bay positions have received attention because they provide a way to red-shift
Nathalie Zink-Lorre +8 more
doaj +1 more source
This is tom = /ZYZYS’tom/ pronunciation in beginners’ EFL textbooks then and now [PDF]
, 2012 The textbook appears to be one of the most fundamental elements of all formal-setting foreign language teaching and learning. Textbooks function in a foreign language classroom in many capacities (Cunningsworth 1995), one of which is the provision of ...
Sobkowiak Włodzimierz
core +1 more source
Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
Advanced Functional Materials, EarlyView.A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
The Living ROMP of trans-Cyclooctene [PDF]
, 2009 The living ring-opening metathesis polymerization (ROMP) of trans-cyclooctene (tCO) was investigated. ROMP of tCO in the presence of PPh_3 in THF leads to the formation of narrowly dispersed polycyclooctene (PCO).
Conrad, Rosemary M. +2 more
core +2 more sources
Diketopyrrolopyrrole Derivatives Functionalized with N-Annulated PDI and Se-Annulated PDI by Direct (Hetero)Arylation Methods [PDF]
Asian Journal of Organic Chemistry, 2020 We report on the synthesis of diketopyrrolopyrrole (DPP) derivatives functionalized with N-annulated and Se-annulated perylene diimide (NPDI and SePDI, respectively) via direct (hetero)arylation methods. DPP is symmetrically bifunctionalized with SePDI (SePDI–DPP–SePDI) and unsymmetrically functionalized with SePDI and NPDI (SePDI–DPP–NPDI).
Thomas A. Welsh +2 more
openaire +1 more source