Results 41 to 50 of about 295,054 (327)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

A Handheld low-mass, impact instrument to measure nondestructive firmness of fruit [PDF]

, 2009
A portable, handheld impact firmness sensor was designed for nondestructive measurement of fruit firmness while the fruit remain attached to the tree or for use in other remote locations where the use of a benchtop instrument would be impractical.
Anderson, M., Chen, P., Ruiz-Altisent, Margarita, Sarig, Y., Slaughter, David, Thompson, J.F.   +5 more
core   +2 more sources

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Understanding the relationship between suicide-related stigma and suicidal thoughts through the lens of the Integrated Motivational-Volitional (IMV) model of suicide

BMC Psychiatry
Background Suicide is a global public health priority and suicide-related stigma is an under-researched but important risk factor, which requires urgent research attention.
J. M. Wyllie, K. A. Robb, R. C. O’Connor   +2 more
doaj   +1 more source

Use of natural environments is associated with reduced inequalities in child mental wellbeing: A cross-sectional analysis using global positioning system (GPS) data

Environment International
Exposure to natural environments may benefit child mental wellbeing whilst offering a lever to reduce health inequalities. However, understanding of these relationships is limited by evidence from indirect measures of exposure.
Fiona Caryl, Paul McCrorie, Jonathan R. Olsen, Richard Mitchell   +3 more
doaj   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

Physical activity, air pollution, and incident long-term conditions: a prospective cohort study

BMC Medicine
Background Physical activity (PA) is consistently associated with lower risk of long-term conditions. Preliminary evidence suggested the associations could be modified by air pollution.
Minshan Huang, Jonathan R. Olsen, Stewart G. Trost, Carlos Celis-Morales, Jill P. Pell, Frederick K. Ho   +5 more
doaj   +1 more source

Suicide-related stigma and its relationship with help-seeking, mental health, suicidality and grief: scoping review

BJPsych Open
Background Suicide-related stigma (i.e. negative attitudes towards people with suicidal thoughts and/or behaviours as well as those bereaved by suicide) is a potential risk factor for suicide and mental health problems.
Jessica M. Wyllie, Kathryn A. Robb, David Sandford, Marianne E. Etherson, Nadia Belkadi, Rory C. O’Connor   +5 more
doaj   +1 more source

Efficient Preservation of Perishable Fruits by Erasable Metal‐Organic Frameworks

Advanced Science, EarlyView.
This study presents an erasable Pickering emulsion‐based coating stabilized by metal‐organic frameworks. This washable coating significantly extends fruit shelf life by scavenging ethylene and inhibiting foodborne pathogens, offering a sustainable solution for postharvest.
Liying Yang, Jia Kong, Haoran Bai, Xiaojie Wu, Douxin Xiao, Ming Du, Peng Yang, Alideertu Dong   +7 more
wiley   +1 more source

Review of Paradox and Platitude in Wittgenstein's Philosophy by David Pears (2006)(review revised 2019) [PDF]

, 2019
Pears is an eminent philosopher, notable among W scholars for his “The False Prison: a study of the development of Wittgenstein’s philosophy” in 2 volumes published 20 years ago.
Starks, Michael
core