Marine Drugs, 2015 The effects of temperature on growth and production of Lipophilic Toxins (LT) by a monoclonal culture of Dinophysis caudata was studied. The cell density of D. caudata increased significantly with increasing temperature, and was the highest under 27, 30,
Satoshi Nagai +2 more
exaly +4 more sources
Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review
Marine Drugs, 2011 Pectenotoxin-2 (PTX-2), which was first identified as a cytotoxic entity in marine sponges, has been reported to display significant cytotoxicity to human cancer cells where it inhibits mitotic separation and cytokinesis through the depolymerization of ...
Yung Hyun Choi +2 more
exaly +4 more sources
In vitro hepatic biotransformation of the algal toxin pectenotoxin-2
Toxicon: X, 2020 We have investigated the in vitro metabolism of pectenotoxin-2 (PTX-2) using primary hepatocytes from Wistar rats in suspension. Purified PTX-2 was rapidly metabolized. Two major and several minor oxidized PTX-2 metabolites were formed, none of which had
Morten Sandvik +3 more
doaj +2 more sources
Co-occurrence of marine and freshwater phycotoxins in oysters, and analysis of possible predictors for management [PDF]
Toxicon: X, 2023 Oysters (Crassostrea virginica) were screened for 12 phycotoxins over two years in nearshore waters to collect baseline phycotoxin data and to determine prevalence of phycotoxin co-occurrence in the commercially and ecologically-relevant species.
Sarah K.D. Pease +12 more
doaj +2 more sources
Growth, Toxin Content and Production of Dinophysis Norvegica in Cultured Strains Isolated from Funka Bay (Japan) [PDF]
Toxins, 2023 The successful cultivation of Dinophysis norvegica Claparède & Lachmann, 1859, isolated from Japanese coastal waters, is presented in this study, which also includes an examination of its toxin content and production for the first time.
Satoshi Nagai +8 more
doaj +2 more sources
Effects of Two Toxin-Producing Harmful Algae, Alexandrium catenella and Dinophysis acuminata (Dinophyceae), on Activity and Mortality of Larval Shellfish [PDF]
Toxins, 2022 Harmful algal bloom (HAB) species Alexandrium catenella and Dinophysis acuminata are associated with paralytic shellfish poisoning (PSP) and diarrhetic shellfish poisoning (DSP) in humans, respectively.
Sarah K. D. Pease +3 more
doaj +2 more sources
Dissolved Algal Toxins along the Southern Coast of British Columbia Canada [PDF]
Toxins, 2023 Harmful algal blooms (HABs) in coastal British Columbia (BC), Canada, negatively impact the salmon aquaculture industry. One disease of interest to salmon aquaculture is Net Pen Liver Disease (NPLD), which induces severe liver damage and is believed to ...
Ryan B. Shartau +6 more
doaj +2 more sources
Integrated Multi-Omics Analysis Reveals Complex Cytotoxicity-Associated Molecular Response Patterns of Representative Toxins from Four Classes of Lipophilic Algal Toxins in Neuro-2a Cells [PDF]
ToxinsLipophilic marine toxins (LMTs) are important toxic risk factors in marine ecosystems and seafood safety, yet the comparative cytotoxicity-associated molecular responses of different LMT classes remain unclear.
Xueru Wei +5 more
doaj +2 more sources
Investigation of Pectenotoxin Profiles in the Yellow Sea (China) Using a Passive Sampling Technique
Marine Drugs, 2010 Pectenotoxins (PTXs) are a group of lipophilic algal toxins. These toxins have been found in algae and shellfish from Japan, New Zealand, Ireland, Norway and Portugal. PTX profiles vary with geographic location of collection site.
Zhaoxin Li +4 more
doaj +2 more sources
Seasonal Single-Site Sampling Reveals Large Diversity of Marine Algal Toxins in Coastal Waters and Shellfish of New Caledonia (Southwestern Pacific) [PDF]
Toxins, 2023 Algal toxins pose a serious threat to human and coastal ecosystem health, even if their potential impacts are poorly documented in New Caledonia (NC).
Manoëlla Sibat +5 more
doaj +2 more sources