Synthesis of the ABC fragment of pectenotoxin-4 [PDF]
, 2012 This thesis details the application of two synthetic methodologies, developed by the Donohoe group, to the synthesis of the ABC fragment of pectenotoxin-4, a macrolide marine natural product that consists of 19 stereogenic centres, three tetrahydrofuran ...
Donohoe, Timothy J. +1 more
core +5 more sources
A novel approach to the synthesis of the FG fragment of pectenotoxin-4 [PDF]
, 2012 The cobalt-catalysed oxidative cyclisation of 5-hydroxy alkenes has been demonstrated to be a powerful synthetic tool for the formation of trans-THFs with excellent diastereoselectivity.
Donohoe, Timothy J +1 more
core +4 more sources
Rhodium-catalysed vinyl 1,4-conjugate addition coupled with Sharpless asymmetric dihydroxylation in the synthesis of the CDE ring fragment of pectenotoxin-4 [PDF]
Chemical Science, 2019 Rhodium and osmium catalysed C–C and C–O bond formation under mild conditions.
Melodie S. W. Richardson +3 more
semanticscholar +2 more sources
A Convergent Route to the CDEF Tetracycle of Pectenotoxin-2 [PDF]
Organic Letters, 2011 A convergent synthesis of the CDEF tetracyclic region of pectenotoxin-2 (PTX-2) is described. The synthetic pathway derives from head-to-tail union of 2 equivalents of linalool to establish a stereodefined DEF tricyclic aldehyde. Subsequent coupling with
Daniel P. Canterbury, G. Micalizio
semanticscholar +3 more sources
Synthesis of the CDE & EFG ring systems of pectenotoxin-4 [PDF]
, 2017 This thesis explores new synthetic routes for the formation of CDE & EFG fragments of pectenotoxin-4. Chapter 1: Introduction and Previous Work This chapter reviews the discovery and biological activities of members of the pectenotoxin family.
Liu, Yifan
core +3 more sources
Effects of Dietary Luteolin on the Growth Performance and Intestinal Health of Juvenile GIFT Tilapia [PDF]
AntioxidantsThis study aimed to investigate the effects of luteolin on the growth performance and intestinal health of juvenile Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus). A total of 450 juvenile GIFT tilapia (initial body weight 8.12 ± 0.04 g)
Xiangli Li +12 more
doaj +2 more sources
Dinophysis acuminata or Dinophysis acuta: What Makes the Difference in Highly Stratified Fjords? [PDF]
Marine Drugs, 2023 Dinophysis acuminata and D. acuta, which follows it seasonally, are the main producers of lipophilic toxins in temperate coastal waters, including Southern Chile.
Ángela M. Baldrich +13 more
doaj +2 more sources
Inhibition of actin polymerization by marine toxin pectenotoxin-2
Journal of Veterinary Medical Science, 2017 Pectenotoxin-2 (PCTX-2) is one of the polyether macrolide toxins isolated from scallops involved in diarrheic shellfish poisoning via actin depolymerization.
M. Hori +7 more
semanticscholar +4 more sources
Synthesis of the C1-C26 Hexacyclic Subunit of Pectenotoxin 2 [PDF]
Organic Letters, 2012 Synthesis of the C1-C26 hexacyclic subunit of pectenotoxin-2 (PTX-2) is described that features a stereoselective annulation to generate the C-ring by triple asymmetric Nozaki-Hiyama-Kishi coupling followed by oxidative cyclization. Preparation of the C1-
Ozora Kubo +2 more
semanticscholar +3 more sources
Chemical Research in Toxicology, 2007 A new pectenotoxin, which has been named pectenotoxin-11 (PTX11), was isolated from the dinoflagellate Dinophysis acuta collected from the west coast of New Zealand.
Suzuki, Toshiyuki +11 more
core +4 more sources