Results 41 to 50 of about 19,606 (267)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Promet (Zagreb), 2004 The problem of minor vehicles crossing or merging into themajor stream at unsignalized priority-controlled intersections iswell-known. Numerous solutions involve various assumptionsconcerning the major headway distributions, number of majorlanes ...
Tomaž Tolazzi
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Assistive Self-Driving Car Networks to Provide Safe Road Ecosystems for Disabled Road Users
Machines, 2023 Disabled pedestrians are among the most vulnerable groups in road traffic. Using technology to assist this vulnerable group could be instrumental in reducing the mobility challenges they face daily.
Juan Guerrero-Ibañez +3 more
doaj +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Frontiers in Human NeuroscienceIntroductionPedestrians are a vulnerable group at the roadside and previous research has identified that children with DCD and ADHD are at a heightened risk of pedestrian injuries.
Rayan Falemban +4 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Traffic Collision Severity Modeling Using Multi-Level Multinomial Logistic Regression Model
Applied SciencesThis study investigates the various factors contributing to the severity of traffic collisions, with specific attention given to elements such as the involvement of pedestrians and cyclists, the roles played by motor vehicles, prevailing weather ...
Rushdi Alsaleh +3 more
doaj +1 more source
Analysis of traffic accidents in children [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2006 Introduction: Violent health damages of different origin (accidents, murders, suicides) in children and youth are one of the main causes of death and disabilities in this group of population in most countries.
Pavlekić Snežana, Puzović Dragana
doaj +1 more source