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Pediatric Acute Liver Failure [PDF]

open access: yesPediatric Reports, 2023
Pediatric acute liver failure (PALF) has recently become a subject of great interest when multiple clusters of non-A to non-E severe acute hepatitis in otherwise healthy young children with a median age of 2 years were reported around the world [...]
Claudia Mandato, Pietro Vajro
doaj   +5 more sources

Prognostic Markers in Pediatric Acute Liver Failure [PDF]

open access: yesGE: Portuguese Journal of Gastroenterology, 2023
Introduction: Acute liver failure (ALF), although rare in children, is a complex progressive pathology, with multisystem involvement and high mortality.
Andreia Filipa Nogueira   +6 more
doaj   +6 more sources

Pediatric acute liver failure: An experience of a pediatric intensive care unit from resource limited settings [PDF]

open access: yesFrontiers in Pediatrics, 2022
IntroductionPediatric acute liver failure is a rare and serious disease. Though liver transplantation is considered as the established treatment option for patients who are unlikely to recover with medical management, however, with the advancement of ...
Puja Amatya   +6 more
doaj   +4 more sources

Pediatric Acute Liver Failure in Sickle Cell Disease [PDF]

open access: yesGE: Portuguese Journal of Gastroenterology, 2021
Introduction: Sickle cell intrahepatic cholestasis (SCIC) is one of the rarest and the most severe acute hepatic manifestations of sickle cell disease (SCD) and it can rapidly progress to acute liver failure.
Luís Rodrigues   +3 more
doaj   +5 more sources

Metagenomic and transcriptomic investigation of pediatric acute liver failure cases reveals a common pathway predominated by monocytes [PDF]

open access: yesmBio
In 2022, a cluster of severe childhood hepatitis was detected primarily in Europe and North America, leading to a global alert by the World Health Organization.
Ruben H. de Kleine   +18 more
doaj   +2 more sources

Development of a prognostic model for pediatric acute liver failure in a Brazilian center [PDF]

open access: yesJornal de Pediatria, 2022
Objective: Pediatric acute liver failure (PALF) is a heterogeneous, rare, and severe condition, which outcome is survival due to liver spontaneous recovery or death.
José Colleti Junior   +4 more
doaj   +2 more sources

Hemostatic Balance in Pediatric Acute Liver Failure: Epidemiology of Bleeding and Thrombosis, Physiology, and Current Strategies [PDF]

open access: yesFrontiers in Pediatrics, 2020
Pediatric Acute Liver Failure (PALF) is a rapidly progressive clinical syndrome encountered in the pediatric ICU which may rapidly progress to multi-organ dysfunction, and on occasion to life threatening cerebral edema and hemorrhage.
Yonca Bulut, Anil Sapru, Gavin D. Roach
doaj   +2 more sources

Prognostic parameters of pediatric acute liver failure and the role of plasma exchange

open access: yesPediatrics and Neonatology, 2019
Background: This study investigated the prognostic parameters and beneficial effects of repeat plasma exchange in children with acute liver failure (ALF).
Mu-Ming Chien   +8 more
doaj   +3 more sources

Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure. [PDF]

open access: yesPLoS ONE, 2013
Tools to predict death or spontaneous survival are necessary to inform liver transplantation (LTx) decisions in pediatric acute liver failure (PALF), but such tools are not available.
Nabil Azhar   +6 more
doaj   +1 more source

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