Results 11 to 20 of about 60,403 (253)

Pediatric Acute Liver Failure in Sickle Cell Disease [PDF]

GE: Portuguese Journal of Gastroenterology, 2021
Introduction: Sickle cell intrahepatic cholestasis (SCIC) is one of the rarest and the most severe acute hepatic manifestations of sickle cell disease (SCD) and it can rapidly progress to acute liver failure.
Luís Rodrigues, Sofia Almeida, Catarina Salgado, Cristina Gonçalves   +3 more
doaj   +3 more sources

[The Importance of Early Referral in Pediatric Acute Liver Failure] [PDF]

Acta medica portuguesa, 2015
INTRODUCTION: Acute liver failure is a rare disorder associated to high morbidity and mortality despite survival improvement through liver transplantation.
Carvalho, L, Farela Neves, J, Furtado, E, Gonçalves, I, Jerónimo, M, Moinho, R, Pinto, C   +6 more
core   +3 more sources

Common mechanisms in pediatric acute liver failure

Trends in Molecular Medicine, 2023
Acute liver failure (ALF) is a rare but potentially fatal disease in children. The etiology is multifactorial, including infection, autoimmune, and genetic disorders, as well as indeterminate hepatitis, which has a higher requirement for liver transplantation.
Jake P. Mann, Dominic Lenz, Zania Stamataki, Deirdre Kelly   +3 more
openaire   +2 more sources

Case Report: Fatal Acute Liver Failure With Giant Cell Transformation in a Pediatric Patient Associated With MIS-C

Frontiers in Pediatrics, 2022
Background: We describe the first pediatric case of a 10-month-old boy with MIS-C who developed fulminant acute liver failure with associated giant cell transformation and a fatal outcome, after ruling out other infectious, metabolic, genetic, and ...
Carolina Bonilla Gonzalez, Marcela Hincapié Echeverría, Rocio Plazas Pachón, Paola Mora Umaña, Berlly Lucia Diaz Gómez, Nathalie Gualdron Barreto   +5 more
doaj   +1 more source

Genetic landscape of pediatric acute liver failure of indeterminate origin [PDF]

Hepatology, 2023
Background and Aims: Pediatric acute liver failure (PALF) is a life-threatening condition. In Europe, the main causes are viral infections (12%–16%) and inherited metabolic diseases (14%–28%). Yet, in up to 50% of cases the underlying etiology remains elusive, challenging clinical management, including liver transplantation. We
Lenz, Dominic, Schlieben, Lea D, Shimura, Masaru, Bianzano, Alyssa, Smirnov, Dmitrii, Kopajtich, Robert, Berutti, Riccardo, Adam, Rüdiger, Aldrian, Denise, Baric, Ivo, Baumann, Ulrich, Bozbulut, Neslihan E, Brugger, Melanie, Brunet, Theresa, Bufler, Philip, Burnytė, Birutė, Calvo, Pier L, Crushell, Ellen, Dalgiç, Buket, Das, Anibh M, Dezsőfi, Antal, Distelmaier, Felix, Fichtner, Alexander, Freisinger, Peter, Garbade, Sven F, Gaspar, Harald, Goujon, Louise, Hadzic, Nedim, Hartleif, Steffen, Hegen, Bianca, Hempel, Maja, Henning, Stephan, Hoerning, Andre, Houwen, Roderick, Hughes, Joanne, Iorio, Raffaele, Iwanicka-Pronicka, Katarzyna, Jankofsky, Martin, Junge, Norman, Kanavaki, Ino, Kansu, Aydan, Kaspar, Sonja, Kathemann, Simone, Kelly, Deidre, Kirsaçlioğlu, Ceyda T, Knoppke, Birgit, Kohl, Martina, Kölbel, Heike, Kölker, Stefan, Konstantopoulou, Vassiliki, Krylova, Tatiana, Kuloğlu, Zarife, Kuster, Alice, Laass, Martin W, Lainka, Elke, Lurz, Eberhard, Mandel, Hanna, Mayerhanser, Katharina, Mayr, Johannes A, McKiernan, Patrick, McClean, Patricia, Mclin, Valérie Anne, Mention, Karine, Müller, Hanna, Pasquier, Laurent, Pavlov, Martin, Pechatnikova, Natalia, Peters, Bianca, Petković Ramadža, Danijela, Piekutowska-Abramczuk, Dorota, Pilic, Denisa, Rajwal, Sanja, Rock, Nathalie, Roetig, Agnès, Santer, René, Schenk, Wilfried, Semenova, Natalia, Sokollik, Christiane, Sturm, Ekkehard, Taylor, Robert W, Tschiedel, Eva, Urbonas, Vaidotas, Urreizti, Roser, Vermehren, Jan, Vockley, Jerry, Vogel, Georg-Friedrich, Wagner, Matias, van der Woerd, Wendy, Wortmann, Saskia B, Zakharova, Ekaterina, Hoffmann, Georg F, Meitinger, Thomas, Murayama, Kei, Staufner, Christian, Prokisch, Holger   +94 more
openaire   +14 more sources

Clinical characteristics of acute liver failure associated with hepatitis A infection in children in Mogadishu, Somalia: a hospital-based retrospective study

BMC Infectious Diseases, 2021
Background Hepatitis A is one of the most common infectious causes of acute hepatitis, and currently, a neglected global public health problem necessitating an urgent response in Somalia.
Esra Keles, Mohamed A. Hassan-Kadle, Marian Muse Osman, Hasan Huseyin Eker, Zeynep Abusoglu, Kursad Nuri Baydili, Aamir Muse Osman   +6 more
doaj   +1 more source

Acute liver failure as a presenting feature in an adolescent with acute lymphoblastic leukemia: A case report with review of literature

Indian Pediatrics Case Reports, 2023
Background: Acute lymphoblastic leukemia (ALL) is a common pediatric malignancy, typically manifesting with symptoms of bone marrow and hematolymphoid organ infiltration.
Simran Bhatnagar, Bharat Kumar, Nitish Kumar, Alok Hemal   +3 more
doaj   +1 more source

Chronic Acetaminophen Exposure in Pediatric Acute Liver Failure [PDF]

Pediatrics, 2013
BACKGROUND: Acetaminophen (N-acetyl-p-aminophenol [APAP]) is a widely used medication that can cause hepatotoxicity. We examined characteristics and outcomes of children with chronic exposure (CE) to APAP in the multinational Pediatric Acute Liver Failure (PALF) Study.
Leonis, Mike A, Alonso, Estella M, Im, Kelly, Belle, Steven H, Squires, Robert H   +4 more
openaire   +3 more sources

Pediatric liver failure: we came, we saw, but have we conquered? [version 1; referees: 2 approved]

F1000Research, 2017
Although there have been advances made in the diagnosis and management of pediatric acute liver failure, there is still no consensus regarding the definition or standardized evaluation, and an inability to predict outcomes, specifically irreversible ...
Sara Kathryn Smith, Philip Rosenthal
doaj   +1 more source

Donor gender does not affect liver transplantation outcome in children [PDF]

, 1990
The liver is recognized as a sex hormone-responsive organ. Gender-specific differences in liver function are known to exist. Recently, a higher failure rate for organs transplanted in adults from female donors to male recipients has been reported.
Gavaler, JS, Pillay, P, Starzl, TE, Van Thiel, DH   +3 more
core   +1 more source