Results 11 to 20 of about 51,344 (275)

Common mechanisms in pediatric acute liver failure [PDF]

Trends in Molecular Medicine, 2022
Acute liver failure (ALF) is a rare but potentially fatal disease in children. The etiology is multifactorial, including infection, autoimmune, and genetic disorders, as well as indeterminate hepatitis, which has a higher requirement for liver ...
Lenz, Dominic, Mann, Jake P; id_orcid, Kelly, Deirdre, Stamataki, Zania   +3 more
core   +3 more sources

Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure. [PDF]

PLoS ONE, 2013
Tools to predict death or spontaneous survival are necessary to inform liver transplantation (LTx) decisions in pediatric acute liver failure (PALF), but such tools are not available.
Nabil Azhar, Cordelia Ziraldo, Derek Barclay, David A Rudnick, Robert H Squires, Yoram Vodovotz, Pediatric Acute Liver Failure Study Group   +6 more
doaj   +3 more sources

Genetic landscape of pediatric acute liver failure of indeterminate origin. [PDF]

Hepatology, 2023
BACKGROUND AIMS Pediatric acute liver failure (PALF) is a life-threatening condition. In Europe, main causes are viral infections (12-16%) and inherited metabolic diseases (14-28%).
Lenz D, Schlieben LD, Schlieben LD, Shimura M, Bianzano A, Smirnov D, Smirnov D, Kopajtich R, Berutti R, Adam R, Aldrian D, Baric I, Baumann U, Bozbulut NE, Brugger M, Brunet T, Bufler P, Burnytė B, Calvo PL, Crushell E, Dalgiç B, Das AM, Dezsőfi A, Distelmaier F, Fichtner A, Freisinger P, Garbade SF, Gaspar H, Goujon L, Hadzic N, Hartleif S, Hegen B, Hempel M, Henning S, Hoerning A, Houwen R, Hughes J, Iorio R, Iwanicka-Pronicka K, Jankofsky M, Junge N, Kanavaki I, Kansu A, Kaspar S, Kathemann S, Kelly D, Kirsaçlioğlu CT, Knoppke B, Kohl M, Kölbel H, Kölker S, Konstantopoulou V, Krylova T, Kuloğlu Z, Kuster A, Laass MW, Lainka E, Lurz E, Mandel H, Mayerhanser K, Mayr JA, McKiernan P, McClean P, McLin V, Mention K, Müller H, Pasquier L, Pavlov M, Pechatnikova N, Peters B, Petković Ramadža D, Piekutowska-Abramczuk D, Pilic D, Rajwal S, Rock N, Roetig A, Santer R, Schenk W, Semenova N, Sokollik C, Sturm E, Taylor RW, Tschiedel E, Urbonas V, Urreizti R, Vermehren J, Vockley J, Vogel GF, Wagner M, van der Woerd W, Wortmann SB, Zakharova E, Hoffmann GF, Meitinger T, Murayama K, Staufner C, Prokisch H.   +96 more
europepmc   +20 more sources

Pediatric liver failure: we came, we saw, but have we conquered? [version 1; referees: 2 approved]

F1000Research, 2017
Although there have been advances made in the diagnosis and management of pediatric acute liver failure, there is still no consensus regarding the definition or standardized evaluation, and an inability to predict outcomes, specifically irreversible ...
Sara Kathryn Smith, Philip Rosenthal
doaj   +3 more sources

Acute Liver Failure Secondary to Niacin Toxicity [PDF]

Case Reports in Pediatrics, 2014
A 17-year-old male was transferred to the pediatric intensive care unit for evaluation of acute liver failure. He was recently released from an alcohol treatment center with acute onset of chest pain.
Marc A. Ellsworth, Katelyn R. Anderson, David J. Hall, Deborah K. Freese, Robin M. Lloyd   +4 more
doaj   +2 more sources

The Importance of Early Referral in Pediatric Acute Liver Failure [PDF]

Acta medica portuguesa, 2015
INTRODUCTION: Acute liver failure is a rare disorder associated to high morbidity and mortality despite survival improvement through liver transplantation.
Carvalho, L, Farela Neves, J, Moinho, R, Furtado, E, Pinto, C, Jerónimo, M, Farela-Neves, J, Gonçalves, I   +7 more
core   +3 more sources

Pediatric acute liver failure: variations in referral timing are associated with disease subtypes

European Journal of Pediatrics, 2015
In pediatric acute liver failure (PALF), rapid referral to a transplant center (TC) is advocated. Clinical variability of PALF may influence referral timing. We aimed to analyze early or late timing of referral in relation to clinical characteristics and
Lexmond, Willem S., Verkade, Henkjan J., Verkade, Henkjan J.; id_orcid, Sturm, Ekkehard   +3 more
core   +4 more sources

Peritransplant care of pediatric acute liver failure

Journal of Pediatric Critical Care
Pediatric acute liver failure (PALF) is a life-threatening clinical syndrome associated with high morbidity and mortality, caused by multiple etiologies. Liver transplantation (LT) remains the definitive treatment for selected patients; however, advances
Ravikumar Thambithurai
doaj   +2 more sources

Acute hepatic failure in pediatric H1N1 infection: a case report from Al-Adan Hospital, Kuwait

Hepatic Medicine: Evidence and Research, 2012
Fawaz Al-RefaeeGastroenterology, Hepatology, and Nutrition Unit, Department of Pediatrics, Al-Adan Hospital, Kuwait City, KuwaitAbstract: Liver involvement in pediatric influenza A (H1N1) infection is rare.
Al-Refaee F
doaj   +1 more source

Pediatric acute liver failure with molecular adsorbent recirculating system treatment

Transplantation Proceedings, 2008
Background. The prognosis of pediatric acute liver failure (PALF) has been significantly improved by emergency orthotopic liver transplantation (OLT).
BERLOCO, Pasquale Bartolomeo, G. Spoletini, ROSSI, MASSIMO, MORABITO, VINCENZO EMILIANO, PUGLIESE, Francesco, MENNINI, Gianluca, S. Novelli, FERRETTI, GIAN CARLO, F. Ruberto, NOVELLI, Gilnardo, S. M. Perrella   +10 more
core   +3 more sources