Etiology and Outcome of Adult and Pediatric Acute Liver Failure in Europe
Acute liver failure (ALF) is rare but life‐threatening. Common causes include intoxications, infections, and metabolic disorders. Indeterminate etiology is still frequent. No systematic data on incidence, causes, and outcome of ALF across Europe are available.
Lenz, Dominic +22 more
openaire +8 more sources
Introduction and Objectives: Acute on chronic liver failure is characterized by acute decompensation of chronic liver disease, associated with different organ failure and, therefore, with high mortality.
Carmen Ana Cerron Cabezas +10 more
doaj +1 more source
Proceedings of ESPGHAN Monothematic Conference 2020: "Acute Liver Failure in Children":Diagnosis and Initial Management [PDF]
OBJECTIVES: The Hepatology Committee of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) aims to educate pediatric gastroenterologists, members of ESPGHAN and professionals from other specialties promoting an ...
Fischler, Björn +50 more
core +1 more source
Immunosuppressive therapy for indeterminate acute hepatitis or pediatric acute liver failure [PDF]
This letter concerns the role of immunosuppressive therapy in the treatment of indeterminate acute liver ...
Maggiore G, Jacquemin E, Bernard O
openaire +2 more sources
Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease. [PDF]
Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify new experimental biomarkers for the detection of CFLD.
Richard Schulz +26 more
core +1 more source
Intravenous N‐acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: A placebo‐controlled clinical trial [PDF]
N‐acetylcysteine (NAC) was found to improve transplantation‐free survival in only those adults with nonacetaminophen (non‐APAP) acute liver failure (ALF) and grade 1‐2 hepatic encephalopathy (HE).
Olio, Dominic Dell +32 more
core +1 more source
NBAS mutations cause acute liver failure: when acetaminophen is not a culprit
Background Pediatric acute-liver-failure due to acetaminophen (APAP) administration at therapeutic dosage is rare, while viral infections and metabolic defects are the prevalent causes. Yet, as acetaminophen is routinely used in febrile illnesses, it may
Pier Luigi Calvo +7 more
doaj +1 more source
A fatal hepatitis A virus with dengue fever co-infection
We report the first pediatric fatal case of Hepatitis A virus (HAV) and dengue virus (DENV) co-infection. A 4-year-old boy who had a partial recovery of HAV infection but with subsequent DENV infection; the condition was complicated by acute fulminant ...
Gassem Gohal
doaj +1 more source
Wilson – Konovalov Disease: Clinical Cases with Different Manifestations and Outcomes
Аim: to describe clinical cases of Wilson – Konovalov disease in pediatric patients.Key points. The first clinical case demonstrates the manifestation of Wilson – Konovalov disease with unexplained mild elevation of aminotransferases at the age of 6 ...
O. V. Samodova +2 more
doaj +1 more source
There are occasional pediatric reports of parvovirus B19-associated transient acute hepatitis and hepatic failure. A case of a 34-year-old immunocompetent woman who developed severe and prolonged but self-limited acute hepatitis and myelosuppression ...
J Kee Ho +7 more
doaj +1 more source

