Results 51 to 60 of about 60,403 (253)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Analysis of Viral Testing in Nonacetaminophen Pediatric Acute Liver Failure [PDF]

Journal of Pediatric Gastroenterology and Nutrition, 2014
ABSTRACTObjective:Viral infections are often suspected to cause pediatric acute liver failure (PALF), but large‐scale studies have not been performed. We analyzed the results of viral testing among nonacetaminophen PALF study participants.Methods:Participants were enrolled in the PALF registry.
Kathleen B, Schwarz, Dominic, Dell Olio, Steven J, Lobritto, M James, Lopez, Norberto, Rodriguez-Baez, Nada A, Yazigi, Steven H, Belle, Song, Zhang, Robert H, Squires   +8 more
openaire   +2 more sources

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Hepatic failure and malnutrition as predisposing factors of cutaneous mucormycosis in a pediatric patient

Medical Mycology Case Reports, 2022
The genus Lichtheimia is the third-most frequent genus isolated in mucormycosis. We report a cutaneous case caused by Lichtheimia ramosa, localized on the face of a pediatric patient, in the context of acute liver failure and caloric malnutrition ...
Silvia Colman, Gustavo Giusiano, Carmen Colman, María de los Ángeles Sosa, Florencia Rojas   +4 more
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Management of Acute Liver Failure in Children

Apollo Medicine
Introduction: Pediatric Acute Liver Failure (PALF) incidence has been increasing in recent times. It is an emergency and needs appropriate management in a specialized center with availability for liver transplant.
Jaswinder Kaur, Smita Malhotra, Karunesh Kumar, Anupam Sibal   +3 more
doaj   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Peritransplant care of pediatric acute liver failure

Journal of Pediatric Critical Care
Pediatric acute liver failure (PALF) is a life-threatening clinical syndrome associated with high morbidity and mortality, caused by multiple etiologies. Liver transplantation (LT) remains the definitive treatment for selected patients; however, advances
Ravikumar Thambithurai
doaj   +1 more source

Diaphragmatic hernia after pediatric living donor liver transplantation: An Indian experience with review of literature

Journal of Indian Association of Pediatric Surgeons, 2021
Aim: Although intestinal obstruction following living donor liver transplantation (LDLT) is relatively common, diaphragmatic hernia (DH) as the attributing cause is rarely reported.
Bramha Pattnaik, Piyush Kumar Sinha, Nilesh Patil Sadashiv, Nihar Mohapatra, Viniyendra Pamecha   +4 more
doaj   +1 more source

Parvovirus B19 infection in pediatric transplant patients [PDF]

, 1993
Evidence of recent parvovirus virus infection (as determined by the presence of a positive IgM antibody titer) without other identified causes of anemia was found in 5 of 26 pediatric solid-organ transplant recipients evaluated for moderate-to-severe ...
Gartner, JC, Green, M, McLoughlin, L, Michaels, M, Nour, B, Reyes, J, Starzl, TE, Tzakis, A   +7 more
core   +1 more source