Results 61 to 70 of about 4,180,741 (282)

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Management of Acute Liver Failure in Children

Apollo Medicine
Introduction: Pediatric Acute Liver Failure (PALF) incidence has been increasing in recent times. It is an emergency and needs appropriate management in a specialized center with availability for liver transplant.
Jaswinder Kaur, Smita Malhotra, Karunesh Kumar, Anupam Sibal   +3 more
doaj   +1 more source

CALFAN (Low γ-Glutamyl Transpeptidase (GGT) Cholestasis, Acute Liver Failure, and Neurodegeneration) Syndrome: A Case Report with 3-Year Follow-Up after Liver Transplantation in Early Adulthood

Case Reports in Hepatology, 2023
CALFAN syndrome is an extremely rare disease consisting of recurrent pediatric acute liver failure (PALF), neurodegenerative diseases, and skeletal abnormalities associated with SCYL1 gene mutation.
Mariam Youssef, Katherine L. Mascia, Brendan McGuire, Chirag R. Patel, Sameer Al Diffalha, Deepti Dhall, Goo Lee   +6 more
doaj   +1 more source

Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial [PDF]

, 2008
: Background Infectious complications and associated mortality are a major concern in acute pancreatitis. Enteral administration of probiotics could prevent infectious complications, but convincing evidence is scarce. Our aim was to assess the effects of
van Eijck, Casper H. J., Rosman, Camiel, Schaapherder, Alexander F. M., Brink, M.A., van Ramshorst, B, Cuesta, Miguel A., van Santvoort, H.C., van Goor, H., Schaapherder, AFM, Besselink, Marc G. H., van der Harst, E, Cuesta, MA, Boermeester, Marja A., Boermeester, MA, van Eijck, CH, Witteman, Ben J. M., Schaapherder, A.F.M., Besselink, MGH, van der Harst, E., Akkermans, Louis M. A., van der Harst, Erwin, Buskens, E., Rosman, C., Dejong, C.H.C., Wahab, Peter J., Laarhoven, C.J.H.M. van, Nieuwenhuijs, V.B., Ploeg, RJ, Besselink, M.G.H., Witteman, BJM, Bollen, TL, Timmerman, Harro M., Timmerman, H.M., van Laarhoven, CJ, Ploeg, R.J., Dejong, CH, Buskens, Erik; id_orcid, Besselink, M.G., van Eijck, Casper, Van Eijck, GHJ, Timmerman, HM, Buskens, E, Gooszen, H.G., Van Laarhoven, CJHM, Akkermans, L.M., Grp, DAPS, Schaapherder, AF, Santvoort, H.C. van, Nieuwenhuijs, VB, Boermeester, M.A., Cuesta, M.A., Nieuwenhuijs, Vincent B., Bollen, T.L., Akkermans, LM, Wahab, PJ, Dejong, CHC, Gooszen, Hein G., van Ramshorst, B., Witteman, B.J., Akkermans, L.M.A., van Laarhoven, C.J.H.M., Dejong, C.H., Dejong, Cornelis H. C., Wahab, P.J., Eijck, C.H. van, van Laarhoven, C.J., Gooszen, HG, van der Harst, E (Erwin), Witteman, B.J.M., Bollen, Thomas L., Harst, E. van der, van Goor, H, Brink, M., van Ramshorst, Bert, Rosman, C, Buskens, Erik, van Laarhoven, Cees J. H. M., Brink, Menno A., Ramshorst, B. van, Ploeg, Rutger, van Goor, Harry, van Eijck, C.H.J., Goor, H. van, Besselink, MG, Brink, MA, Schaapherder, A.F., Akkermans, LMA, van Eijck, C.H., van Santvoort, HC, van Santvoort, Hjalmar C., Witteman, BJ, van Eijck, van, Ploeg, Rutger J.   +92 more
core   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Acute liver failure associated with prolonged use of bromfenac leading to liver transplantation [PDF]

, 1999
Bromfenac, a nonnarcotic analgesic nonsteroidal anti-inflammatory drug, was associated with reversible, minor elevations in serum aminotransferase levels during clinical trials.
Gunartanam, Naresh T, Lee, William M, Rabkin, John M., McCashland, Timothy M., Benner, Kent G, Fontana, Robert John, Acute Liver Failure Study Grp, Gunartanam, Naresh T., Wisecarver, James L, Appelman, Henry D., Lee, William M., McCashland, Timothy M, Rabkin, John M, Wisecarver, James L., Fontana, Robert J, Benner, Kent G., Appelman, Henry D   +16 more
core   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

Living donor liver transplantation for acute liver failure in pediatric patients caused by the ingestion of fireworks containing yellow phosphorus

, 2011
Yellow phosphorus is a protoplasmic toxicant that targets the liver. The ingestion of fireworks containing yellow phosphorus, either by children who accidentally consume them or by adults who are attempting suicide, often results in death due to acute ...
Işık, Burak, Selimoğlu, Mukadder Ayşe, Kayaalp, Cüneyt, Yılmaz, Sezai, Aydın, Cemalettin, Ara, Cengiz, Ateş, Mustafa, Yılmaz, Mehmet, Özgör, Dinçer, Dirican, Abuzer   +9 more
core   +1 more source

Hepatic failure and malnutrition as predisposing factors of cutaneous mucormycosis in a pediatric patient

Medical Mycology Case Reports, 2022
The genus Lichtheimia is the third-most frequent genus isolated in mucormycosis. We report a cutaneous case caused by Lichtheimia ramosa, localized on the face of a pediatric patient, in the context of acute liver failure and caloric malnutrition ...
Silvia Colman, Gustavo Giusiano, Carmen Colman, María de los Ángeles Sosa, Florencia Rojas   +4 more
doaj   +1 more source

Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy [PDF]

, 2004
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whom hepatorenal syndrome is common.
Jalan, R., Hayes, P.C., Mookerjee, R.P., Shawcross, D.L., Williams, R., Lee, A., Davies, N.A.   +6 more
core