Results 101 to 110 of about 4,180,741 (282)

Acute Hepatic Failure Caused by Hepatitis B Virus Reactivation in Patients Receiving Immunomodulatory Agents for Autoimmune Diseases

open access: yes, 2017
Objectives: The increasing use of novel immunomodulators, such as rituximab, leflunomide and adalimumab in the treatment of autoimmune diseases may put hepatitis B virus (HBV) carriers at increased risk for reactivation and consequent hepatic failure ...
胡瑞恒;何承懋;賴鴻緒;李伯皇   +1 more
core   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

open access: yesAdvanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong   +5 more
wiley   +1 more source

Assessment of Prognostic Factors of Acute Hepatitis Among Pediatric Patients: A Cross‐Sectional Study

open access: yesJGH Open
Introduction Early identification of acute hepatitis etiology and specific management is crucial for reducing morbidity and mortality. Therefore, this study aims to investigate the prognostic factors of acute hepatitis in children.
Neda Ezoddin   +5 more
doaj   +1 more source

Central venous line associated osteomyelitis in children with intestinal failure

open access: yesJournal of Pediatric Surgery Case Reports, 2018
Children with intestinal failure often require long-term central venous access for parenteral nutrition. Line-related complications often include liver dysfunction, sepsis, and loss of venous access.
Teresa Yu   +6 more
doaj   +1 more source

Predicting acute cellular rejection after liver transplantation: form liver function test to immune monitoring [PDF]

open access: yes, 2013
In recent years, the main end point of immunosuppressive therapy after liver transplantation has moved from the prevention of acute cellular rejection (ACR) toward the preservation of long-term graft function and prevention of immunosuppression-related ...
Germani, Giacomo
core  

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng   +14 more
wiley   +1 more source

Case Report: Conservative management of hemophagocytic lymphohistiocytosis with fulminant hepatic failure in a pediatric leukemia patient

open access: yesFrontiers in Pediatrics
IntroductionHemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome that can lead to multiorgan failure, including acute liver failure.
Filipa Paixão   +4 more
doaj   +1 more source

Fallo hepático aguda asociado a enfermedades metabólicas hereditarias en niños pequeños

open access: yesAnales de Pediatría, 2018
Resumen: Introducción: El fallo hepático agudo (FHA) secundario a enfermedades metabólicas hereditarias (EMH) es una enfermedad grave infrecuente de mal pronóstico. La intervención temprana puede salvar vidas. Objetivo: Describir la presentación clínica,
Filipa Dias Costa   +6 more
doaj   +1 more source

Acute Liver Failure: A Dangerous and Challenging Syndrome [PDF]

open access: yes, 2014
Despite progress in understanding the underlying mechanisms, acute liver failure (ALF) is still one of the major clinical challenges in hepatology. A wide variety of aetiologies, and similarly, variable courses of the disease, make it crucial to identify
Guido Gerken, Ali Canbay
core  

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

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