Comparison of Two Donor Liver Procurement Methods for Treatment of Pediatric Acute Liver Failure [PDF]
Frontiers in Pediatrics, 2022 BackgroundTo evaluate the difference and efficacy of two donor liver procurement methods for treatment of pediatric acute liver failure (PALF) by living donor liver transplantation (LDLT).MethodsA total of 17 patients (12 men, 5 women) with PALF who ...
Jiahao Pei +7 more
doaj +2 more sources
[The Importance of Early Referral in Pediatric Acute Liver Failure] [PDF]
Acta medica portuguesa, 2015 INTRODUCTION: Acute liver failure is a rare disorder associated to high morbidity and mortality despite survival improvement through liver transplantation.
Carvalho, L +6 more
core +3 more sources
Transcriptional Analysis of Liver Tissue Identifies Distinct Phenotypes of Indeterminate Pediatric Acute Liver Failure [PDF]
Hepatology Communications, 2021 Many patients with indeterminate pediatric acute liver failure (PALF) have evidence of T‐cell driven immune injury; however, the precise inflammatory pathways are not well defined. We have characterized the hepatic cytokine and transcriptional signatures
Catherine A Chapin +10 more
doaj +2 more sources
Liver Transplant Listing in Pediatric Acute Liver Failure: Practices and Participant Characteristics. [PDF]
Hepatology, 2018 Liver transplant (LT) decisions in pediatric acute liver failure (PALF) are complex. Three phases of the PALF registry, containing data on 1,144 participants over 15 years, were interrogated to characterize clinical features associated with listing status. A decrease in the cumulative incidence of listing ( P
Squires JE +7 more
europepmc +4 more sources
Pediatric acute liver failure of undetermined cause: A research workshop. [PDF]
Hepatology, 2017 Pediatric acute liver failure (PALF) is a potentially devastating condition that occurs in previously healthy children of all ages and frequently leads to a rapid clinical deterioration. An identified cause for liver injury is lacking in approximately 30% of cases. Children with undetermined diagnosis have lower spontaneous survival and higher rates of
Alonso EM +3 more
europepmc +4 more sources
Acute liver failure secondary to Ayurvedic Herbal medication in a child: a case report [PDF]
Asia Pacific Journal of Medical Toxicology, 2021 Ayurvedic and Herbal medicine induced liver injury is rarely reported in children. The injury can range from mild asymptomatic elevation of liver enzymes to severe presentation with acute liver failure leading to death.
Sagar Mehta +4 more
doaj +1 more source
Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure. [PDF]
PLoS ONE, 2013 Tools to predict death or spontaneous survival are necessary to inform liver transplantation (LTx) decisions in pediatric acute liver failure (PALF), but such tools are not available.
Nabil Azhar +6 more
doaj +1 more source
Frontiers in Pediatrics, 2022 Management of acute liver failure (ALF) and acute on chronic liver failure (ACLF) in the pediatric population can be challenging. Kidney manifestations of liver failure, such as hepatorenal syndrome (HRS) and acute kidney injury (AKI), are increasingly ...
Rupesh Raina +36 more
doaj +1 more source
Common mechanisms in pediatric acute liver failure
Trends in Molecular Medicine, 2023 Acute liver failure (ALF) is a rare but potentially fatal disease in children. The etiology is multifactorial, including infection, autoimmune, and genetic disorders, as well as indeterminate hepatitis, which has a higher requirement for liver transplantation.
Jake P. Mann +3 more
openaire +2 more sources
The Turkish Journal of Pediatrics, 2023 Background. Liver transplantation (LT) is a well-established, life-saving treatment for children with irreversible acute and chronic liver failure (LF).
Edin Botan +14 more
doaj +1 more source