Results 111 to 120 of about 1,645,101 (196)

Pediatric adrenocortical tumor in a 17-month-old girl: Diagnostic and therapeutic challenges in a rare case of virilization

Chronic Diseases Journal
BACKGROUND: Adrenocortical tumors (ACTs) are extremely uncommon in children. These tumors predominantly secrete hormones, leading to significant clinical manifestations, including peripheral precocious puberty and virilization.
Borhan Moradveisi, Mobin Azami, Jila Yousofi, Sepideh Haddadi   +3 more
doaj   +1 more source

Supplementary Table 1 from Prognostic Significance of Major Histocompatibility Complex Class II Expression in Pediatric Adrenocortical Tumors: A St. Jude and Children's Oncology Group Study

, 2016
Clinical Data for Pediatric Adrenocortical Tumor ...
Bonald C. Figueiredo (10967868), Emilia Modolo Pinto (15010437), Stanley Pounds (141561), Zhifa Liu (6000437), David Finkelstein (222792), Carlos Rodriguez-Galindo (27342), Geoffrey Neale (47090), Alberto S. Pappo (14953824), Raul C. Ribeiro (14944464), John Kim Choi (15010440), Gerard P. Zambetti (14881968), John M. Hicks (14924156)   +11 more
core   +1 more source

Atypical presentation of a hormonally active adrenocortical tumor in an adolescent leading to delayed diagnosis

, 2011
Adrenocortical tumors are rare in children and present with variable signs depending on the type of hormone excess. We herein describe the unusual presentation of a child with adrenocortical tumor and introduce the concept of in vitro chemosensitivity ...
Mullis, Primus E, Zanolari Calderari, Maura, Flück, Christa E, Cree, Ian, Hagemann, Kerstin, Perren, Aurel   +5 more
core  

Characterization of p53 p.T253I as a pathogenic mutation underlying Li-Fraumeni Syndrome.

PLoS ONE
We identified a germline TP53 c.758C > T (p.T253I) mutation in the TP53 tumor suppressor gene in a pediatric adrenocortical carcinoma (ACC) patient. Characteristic of pathogenic p53 mutations, we observed upregulation of total p53 protein levels in the ...
Nathaniel C Holcomb, Amanda M Harrington, Hong Pu, Berina Halilovic, Nathan R Shelman, Shulin Zhang, Catherine Sears, Terra Armstrong, Brent Shelton, Lauren Corum, John A D'Orazio   +10 more
doaj   +1 more source

Pediatric Phantom Dosimetry of Kodak 9000 Cone-beam Computed Tomography

, 2017
Purpose: The purpose of the study was to evaluate the radiation dose of the Kodak 9000 cone-beam computed tomography (CBCT) device for different anatomical areas using a pediatric phantom.
Ehrlich, Ygal, Sanders, Brian J., Yepes, Juan F., Jones, James E., Johnson, Brandon, Ludlow, John B., Booe, Megan R.   +6 more
core   +1 more source

A proteome-based classification of pediatric adrenocortical tumors links functional tumor states to clinical outcome and therapeutic vulnerabilities

Abstract Pediatric adrenocortical tumors (pACT) are biologically heterogeneous and incompletely classified by histopathology. To elucidate proteome-level tumor organization, we performed mass spectrometry–based proteomic profiling of 83 pACT and 43 normal adrenal samples.
Rainer Claus, Andreas Metousis, Victoria E. Fincke, Marina Kunstreich, Stefan A. Wudy, Eva Jüttner, Joern Pons-Kühnemann, Christian Vokuhl, Michael C. Frühwald, Christoph Röcken, Lisa Schweizer, Pascal D. Johann, Antje Redlich, Matthias Mann, Michaela Kuhlen   +14 more
openaire   +1 more source

Comparison of clinical characteristics between children and adults with adrenal mass. [PDF]

Discov Oncol
Song J, Zhang K, Han S, Chao M, Zhang Y, Chen X.   +5 more
europepmc   +1 more source

Suramin in adrenocortical cancer [PDF]

, 1994
Winkelmann, W., Arlt, W., Siekmann, L., Allolio, B., Reincke, Martin   +4 more
core   +1 more source

Pre-operative control of arterial hypertension using ketoconazole in pediatric patients with adrenocortical tumors

, 2015
Adrenocortical tumors are rare in childhood, appearing more frequently in some regions such as South and South-eastern regions of Brazil and India. Common clinical signs include virilization, Cushing's syndrome, feminization and hypertension, either ...
Koler, H, Goncalves, A, Marini, SHVD, Bustorff-Silva, JM, Epelman, S, Guerra, G, Neto, LS   +6 more
core  

Li-Fraumeni Syndrome: Current Perspectives on Molecular Pathogenesis, Surveillance Strategies, Clinical Management and Pediatric Considerations. [PDF]

Cureus
Graifman G, Currie S, Parekh R, C P RV, Nair A.   +4 more
europepmc   +1 more source