Results 21 to 30 of about 4,767,425 (261)

Malignant sacro-coccygeal teratoma with growing teratoma syndrome

Journal of Pediatric Surgery Case Reports, 2019
A 13-month-old female with sacro-coccygeal tumor type II by Altman, was proven by biopsy to be a malignant germ cell tumor. Serum tumor markers were normal.
Tamador Al-Shamaileh, Fatena Ajlouni, Rasha Deebajah, Iyad Sultan, Mohammad M. Saleem, Khalil Ghandour   +5 more
doaj   +1 more source

Alleviating Terminal Pediatric Cancer Pain

, 2021
Terminal cancer pain remains one of the most distressing aspects of pediatric oncology practice. Opioids are the cornerstone of cancer pain management at end-of-life and fortunately, most pain at end-of-life can be managed successfully.
Veronica Carullo, Karen Moody, Mohammad Baig   +2 more
core   +1 more source

The unveiled face of IEI: Children Cancer Hospital—Egypt (CCHE-57357) experience

Frontiers in Immunology
BackgroundInborn errors of immunity (IEI) are a heterogeneous group of different disorders characterized by a defect in the function and/or components of the immune system.
Nesrine Radwan, Nesrine Radwan, Youssef Medany, Youssef Medany, Hanaa Rashad, Ahmed Elhemaly, Ahmed Elhemaly, Mahmoud Hammad, Mahmoud Hammad, Hany Abdel Rahman, Hany Abdel Rahman, Mona Fakhry, Nora Mahmmoud Marouf, Ahmed Mahdy, Mariam Elsherif, Maram Farouk Salama, Nesreen Ali, Nesreen Ali, Sally Talaat, Sally Talaat, Seham Gohar, Ahmed Emad, Iman Sidhom, Iman Sidhom, Nahla EL-Sharkawy, Nahla EL-Sharkawy, Alaa El-Haddad, Alaa El-Haddad   +27 more
doaj   +1 more source

Targeting SWI/SNF ATPases reduces neuroblastoma cell plasticity

The EMBO Journal
Tumor cell heterogeneity defines therapy responsiveness in neuroblastoma (NB), a cancer derived from neural crest cells. NB consists of two primary subtypes: adrenergic and mesenchymal.
Man Xu, Jason J Hong, Xiyuan Zhang, Ming Sun, Xingyu Liu, Jeeyoun Kang, Hannah Stack, Wendy Fang, Haiyan Lei, Xavier Lacoste, Reona Okada, Raina Jung, Rosa Nguyen, Jack F Shern, Carol J Thiele, Zhihui Liu   +15 more
doaj   +1 more source

The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers

Nature Communications, 2017
SWI/SNF chromatin remodelling complex is a major regulator of chromatin structure and of transcription. Here, using mouse embryonic fibroblasts and human rhabdoid tumour cells, the authors provide evidence that SWI/SNF functions as a regulator of ...
Burak H. Alver, Kimberly H. Kim, Ping Lu, Xiaofeng Wang, Haley E. Manchester, Weishan Wang, Jeffrey R. Haswell, Peter J. Park, Charles W. M. Roberts   +8 more
doaj   +1 more source

Omega-3 Fatty Acids and Their Role in Pediatric Cancer

, 2021
Background: Malnutrition is common in children with cancer and is associated with adverse clinical outcomes. The need for supportive care is becoming ever more evident and the role of nutrition in oncology is still not sufficiently understood.
Alexandra Podpeskar, Roman Crazzolara, Bernhard Meister, Christina Salvador, Thomas Müller, Benjamin Hetzer, Gabriele Kropshofer   +6 more
core   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Evaluation of Claim Reports for Potential Impact of COVID-19 on Pediatric Dental Procedures [PDF]

, 2023
Purpose: To evaluate whether the postponement of dental elective procedures at the start of the COVID-19 pandemic was associated with an increased number of simple dental extractions, and/or decreased restorative procedures by analyzing data obtained ...
Vinson, LaQuia, Bauer, Brittany A., Sanders, Brian J., Eckert, George, Yepes, Juan F.   +4 more
core   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

MYCN and KAT2A form a feedforward loop to drive an oncogenic transcriptional program in neuroblastoma

Oncogenesis
The oncoprotein MYCN drives malignancy in various cancer types, including neuroblastoma (NB). However, our understanding of the mechanisms underlying its transcriptional activity and oncogenic function, as well as effective strategies to target it ...
Zhihui Liu, Jason J. Hong, Xiyuan Zhang, Carly M. Sayers, Wendy Fang, Man Xu, Sydney Loria, Sakereh Maskal, Haiyan Lei, Haitao Wu, Rolf Swenson, Jordan L. Meier, Jack F. Shern, Carol J. Thiele   +13 more
doaj   +1 more source