Results 41 to 50 of about 4,767,425 (261)

Pediatric Thyroid Cancer: To Whom Do You Send the Referral?

, 2021
Pediatric thyroid cancer is rare, but increasing in annual incidence. Differentiated thyroid cancer in pediatric patients is treated surgically. Pediatric thyroidectomies are performed by general surgeons, otolaryngologists, general pediatric surgeons ...
Darrin V. Bann, Allison Keane, David Goldenberg, Meghan N. Wilson   +3 more
core   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma

Cell Death and Disease
MYCN amplification is an independent poor prognostic factor in patients with high-risk neuroblastoma (NB). Further exploring the molecular regulatory mechanisms in MYCN-amplified NB will help to develop novel therapy targets.
Jinqiu Guan, Mengzhen Li, Yi Wang, Yu Zhang, Yi Que, Suying Lu, Juan Wang, Jia Zhu, Junting Huang, Zijun Zhen, Feifei Sun, Mengjia Song, Yizhuo Zhang   +12 more
doaj   +1 more source

Pediatric Phantom Dosimetry Evaluation of the Extraoral Bitewing

, 2020
Purpose: This study’s purpose was to evaluate the effective dose (E) and equivalent dose (HT) of exposing a pediatric phantom to the extraoral bitewing programs of the Planmeca ProMax 2D S3 (ProMax) and Instrumentarium Orthopantomograph OP30 (OP30) and ...
Tang, Qing, Wiley, Dillon, Sanders, Brian J., Yepes, Juan F., Jones, James E., Johnson, K. Brandon   +5 more
core  

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression

BMC Bioinformatics, 2019
Background With the advent of array-based techniques to measure methylation levels in primary tumor samples, systematic investigations of methylomes have widely been performed on a large number of tumor entities. Most of these approaches are not based on
Pascal David Johann, Natalie Jäger, Stefan M. Pfister, Martin Sill   +3 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Pediatric NUT carcinoma: a patient series and literature review

BMC Pediatrics
Background Nuclear protein in testis (NUT) carcinoma (NC) in children is a rare tumor with highly aggressive nature and dismal prognosis. Methods We conducted a retrospective analysis of case series towards NC-patients aged 0–18 years treated at the ...
Yalan You, Suying Lu, Feifei Sun, Xiangling He, Juan Wang, Junting Huang, Yi Que, Zijun Zhen, Yizhuo Zhang, Jia Zhu   +9 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Epidemiological Features of Childhood Acute Leukemia at MAHAK’s Pediatric Cancer Treatment and Research Center (MPCTRC), Tehran, Iran

Basic & Clinical Cancer Research, 2015
Aims: MAHAK’s Pediatric Cancer Treatment and Research Center (MPCTRC) is one of the main national referral centers for childhood malignancies. Due to large number of referrals, data compiled at this center can consider as reference for any issues related
Azim Mehrvar, Mohammad Faranoush, Amir Abbas Hedayati Asl, Maryam Tashvighi, Mohammad Ali Fazeli, Narjes Mehrvar, Rokhsaneh Zangooie, Afarin Sadeghian, Ali Jafarpour, Behdad Sobuti, Mardawig Alebouyeh, Parvaneh Vossough   +11 more
doaj