Results 61 to 70 of about 6,542,588 (257)

Incidence of Growth Hormone Deficiency in Pediatric-Onset Langerhans Cell Histiocytosis: Efficacy and Safety of Growth Hormone Treatment [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2004
We retrospectively studied 61 patients with GH deficiency (GHD), identified among 589 patients with Langerhans cell histiocytosis (LCH) enrolled in a nationwide survey between 1993 and 2001. Overall, 141 patients in the survey developed diabetes insipidus. The median follow-up of the 61 patients with GHD was 12 yr.
Jean, Donadieu, Maria-Alejandra, Rolon, Isabelle, Pion, Caroline, Thomas, François, Doz, Mohamed, Barkaoui, Alain, Robert, Anne, Deville, Françoise, Mazingue, Michel, David, Raja, Brauner, Sylvie, Cabrol, Catherine, Garel, Michel, Polak   +13 more
openaire   +2 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Growth hormone replacement therapy in adults with growth hormone deficiency improves vascular reactivity

, 1999
Patients with adult growth hormone (GH) deficiency are thought to be of increased risk of cardiovascular disease. Impaired vascular reactivity to endothelium derived nitric oxid (NO) is an early event in the development of atherosclerosis.
Russell-Jones, D L, Christ, E R, Sönksen, P H, Russel-Jones, D L, Chowienczyk, P J, Peter H. Sönksen, Emanuel R. Christ, Philip J. Chowienczyk, David L. Russel-Jones   +8 more
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

SETD5 gene mutation as the cause of short stature

Pediatria Polska
An 8-year-old boy was referred to the Clinic of Pediatric Endocrinology due to his short stature. The child comes from P II B II, was born naturally, with birth weight 2970 g. He had dysmorphism and a height of 118 cm (3rd centile).
Aleksandra Maria Roztoczyńska, Dorota Roztoczyńska, Antoni Pyrkosz, Artur Mazur   +3 more
doaj   +1 more source

Dental management of isolated growth hormone deficiency: A case report

, 2005
In case of growth hormone deficiency, periodontal problems may accompany due to the abnormal formation of teeth making plaque accumulation easier. The purpose of this report is to describe dental management of a 14-year old female patient with isolated ...
Alpoz A.R., Yetkiner E., Kardesler L., Buduneli N., Candan U.   +4 more
core   +1 more source

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo, Claudia Dosi, Stefano Parravicini, Riccardo Zanin, Marta Cheli, Eleonora Giacopuzzi Grigoli, Amalia Canciello, Francesca Andreetta, Riccardo Masson, Silvia Bonanno, Stefania Marcuzzo, Lorenzo Maggi   +11 more
wiley   +1 more source

Improving growth and development in children with growth hormone deficiency through transdermal treatment of acupoints with the tonifying spleen and kidney method in conjunction with growth hormone therapy

Pakistan Journal of Pharmaceutical Sciences
This retrospective analysis aimed to evaluate the potential benefits of integrating transdermal acupoint therapy with the tonifying spleen and kidney method alongside growth hormone (GH) treatment for pediatric patients suffering from growth hormone ...
Huming Yang, Qingdan Yuan
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) [PDF]

Annals of Pediatric Endocrinology & Metabolism
The Kabi International Growth Study (KIGS) was first established in 1987 and is the largest pharmaco-epidemiological study of recombinant human growth hormone (rhGH).
Mitchell E. Geffner, Michael B. Ranke, Michael P. Wajnrajch, for the Pfizer International Growth Database Strategic Executive Committee, Strategic Advisory Board, and International Board   +3 more
doaj   +1 more source