Results 61 to 70 of about 23,786 (267)

Growth Hormone Deficiency in a Patient with Becker Muscular Dystrophy: A Pediatric Case Report [PDF]

Case Reports in Endocrinology, 2013
Objective. To describe a biochemical growth hormone (GH) deficiency and to evaluate therapeutic result in a six-year-old male with Becker muscular dystrophy (BMD).Methods. GH peak was evaluated after response to arginine and insulin. Bone age was evaluated according to Greulich and Pyle method.Results. The GH-supplementary therapy was very effective in
CALCATERRA, VALERIA, BOZZOLA, MAURO, LARIZZA, DANIELA, Malvezzi A., Toglia R., Berardinelli A., Bozzola E.   +6 more
openaire   +4 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

SETD5 gene mutation as the cause of short stature

Pediatria Polska
An 8-year-old boy was referred to the Clinic of Pediatric Endocrinology due to his short stature. The child comes from P II B II, was born naturally, with birth weight 2970 g. He had dysmorphism and a height of 118 cm (3rd centile).
Aleksandra Maria Roztoczyńska, Dorota Roztoczyńska, Antoni Pyrkosz, Artur Mazur   +3 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Improving growth and development in children with growth hormone deficiency through transdermal treatment of acupoints with the tonifying spleen and kidney method in conjunction with growth hormone therapy

Pakistan Journal of Pharmaceutical Sciences
This retrospective analysis aimed to evaluate the potential benefits of integrating transdermal acupoint therapy with the tonifying spleen and kidney method alongside growth hormone (GH) treatment for pediatric patients suffering from growth hormone ...
Huming Yang, Qingdan Yuan
doaj   +1 more source

An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) [PDF]

Annals of Pediatric Endocrinology & Metabolism
The Kabi International Growth Study (KIGS) was first established in 1987 and is the largest pharmaco-epidemiological study of recombinant human growth hormone (rhGH).
Mitchell E. Geffner, Michael B. Ranke, Michael P. Wajnrajch, for the Pfizer International Growth Database Strategic Executive Committee, Strategic Advisory Board, and International Board   +3 more
doaj   +1 more source

ODP392 Persistence with daily growth hormone treatment among pediatric patients with growth hormone deficiency in the UK

Journal of the Endocrine Society, 2022
Abstract Background Suboptimal adherence to, and persistence with, daily somatropin therapy to treat children with growth hormone deficiency (GHD) has been documented previously, and has also been shown to have negative effects on the growth response ...
Loftus, Jane, Wogen, Jen, Oliveri, David, Benjumea, Darrin, Jhingran, Priti, Chen, Yong, Alvir, Jose, Sanz, Elena Rivero, Kowalik, Jack Charles   +8 more
openaire   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Response to growth hormone treatment in very young patients with growth hormone deficiencies and mini-puberty [PDF]

, 2018
Background: The aim of the study was to assess the response to growth hormone (GH) treatment in very young patients with GH deficiency (GHD) through a national, multi-center study. Possible factors affecting growth response were assessed (especially mini-
Siklar, Zeynep, Firdevs Baş, Semih Bolu, Şenay Savaş Erdeve, Ozbek, Mehmet Nuri, Zeynep Şıklar, Jones, Filiz Mine Cizmecioglu, Erdeve, Senay Savas, Şıklar, Zeynep, Darcan, Sukran, Feyza Darendeliler, Filiz Mine Çizmecioğlu Jones, Esra Deniz Papatya, Aycan, Zehra, Adal, Erdal, Darendeliler, Feyza, Şükran Poyrazoğlu, Metin Yıldız, Mehmet Nuri Özbek, Abaci, Ayhan, Yıldız, Metin, Abacı, Ayhan, ABALI, Saygın, Jones, FİLİZ MİNE, Şükran Darcan, Poyrazoglu, Sukran, Cetinkaya, Semra, Bolu, Semih, Muammer Büyükinan, Abdullah Bereket, Bereket, Abdullah, Mengen, Eda, Simsek, Enver, Erdal Adal, Abalı, Saygın, Tayfun, Meltem, Zehra Aycan, Papatya, Esra Deniz, Merih Berberoğlu, Darendeliler, Fatma Feyza, Yildiz, Metin, Meltem Tayfun, İffet Bircan, Enver Şimşek, Ercan, Oya, Buyukinan, Muammer, Bircan, Iffet, Semra Çetinkaya, Saygın Abalı, Eda Mengen, ÇİZMECİOĞLU JONES, FİLİZ MİNE, Bas, Firdevs, Abali, Saygin, Ayhan Abacı, Berberoglu, Merih, Oya Ercan   +55 more
core   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source