Results 71 to 80 of about 23,786 (267)

Retinal Neural and Vascular Structure in Isolated Growth Hormone Deficiency Children and Evaluation of Growth Hormone Treatment Effect [PDF]

, 2018
To evaluate neural and vascular retinal morphology of children with isolated growth hormone deficiency (GHD) and to determine any retinal changes due to GH ...
Hamdi Cihan Emeksiz, Orhun Çamurdan, Döğer, E., Zeynep Aktaş, Yalçın, N.G., Yüce, Ö., Çamurdan, Orhun, Yüce, Özge, Peyami Cinaz, Bideci, A., Çamurdan, O., Aktaş, Zeynep, Yalçın, Nuriye Gökçen, Hasanreisoğlu, M., Döğer, Esra, Özge Yüce, Aysun Bideci, Aktaş, Z., Emeksiz, Hamdi Cihan, Cinaz, Peyami, Esra Döğer, Cinaz, P., Nuriye Gökçen Yalçın, Bideci, Aysun, Murat Hasanreisoğlu, Emeksiz, H.C., Hasanreisoğlu, Murat   +26 more
core   +1 more source

Pre- and postdiagnosis growth failure, adult short stature, and untreated growth hormone deficiency in radiotherapy-treated long-term survivors of childhood brain tumor.

PLoS ONE, 2022
PurposeGrowth failure is common in radiotherapy-treated long-term survivors of pediatric brain tumors, but studies on longitudinal growth in this patient group are lacking. Here, the aim was to assess the changes in growth patterns before and after brain
Julia Anttonen, Tiina Remes, Pekka Arikoski, Päivi Lähteenmäki, Mikko Arola, Arja Harila-Saari, Tuula Lönnqvist, Tytti Pokka, Pekka Riikonen, Kirsti Sirkiä, Heikki Rantala, Marja Ojaniemi   +11 more
doaj   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

CROSS-TALK BETWEEN ENDOCRINE SYSTEM AND OTHER BIOLOGICAL PATHWAYS: PHYSIOLOGICAL AND PATHOLOGICAL IMPLICATIONS IN PAEDIATRIC ENDOCRINOPATHIES [PDF]

, 2009
Endocrine system exerts relevant effects on multiple organs and tissues. Pleiotropic and redundant functions of circulating hormones are due to the various receptors expressed on multiple target cells.
Capalbo, Donatella
core  

Adherence and Patient Satisfaction in Children Receiving Long-Acting vs. Daily Growth Hormone Therapy: A Single-Center Study

International Journal of Pediatrics & Adolescent Medicine
Objectives Growth hormone deficiency (GHD) in children is a significant medical condition that impairs growth and development, necessitating early intervention to mitigate potential long-term health consequences. This study aimed to assess aspects of the
Nouf M. Alnosani, Abdulmoein Al-Agha
doaj   +1 more source

Pituitary Morphology and Function in 43 Children with Central Diabetes Insipidus

International Journal of Endocrinology, 2016
Objective. In pediatric central diabetes insipidus (CDI), etiology diagnosis and pituitary function monitoring are usually delayed. This study aimed to illustrate the importance of regular follow-up and pituitary function monitoring in pediatric CDI ...
Wendong Liu, Limin Wang, Minghua Liu, Guimei Li   +3 more
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Optimization of bone health in children before and after renal transplantation: current perspectives and future directions

Frontiers in Pediatrics, 2014
The accrual of healthy bone during the critical period of childhood and adolescence sets the stage for lifelong skeletal health. However, in children with chronic kidney disease (CKD), disturbances in mineral metabolism and endocrine homeostasis begin ...
Kristen eSgambat, Asha eMoudgil
doaj   +1 more source

Pediatric growth hormone deficiency: Understanding the patient and caregiver perspectives

Growth Hormone & IGF Research
Childhood growth hormone deficiency (GHD) is a rare disorder associated with significant burden on both patients and caregivers. Although previous reports have detailed aspects of the burden experienced by patients and their caregivers, there is a paucity of first-hand information on the patient and caregiver journeys from their respective voices.
Bradley S, Miller, Nicky, Kelepouris, Harlan, Tenenbaum, Sonia, Di Carlo, Philippe, Backeljauw   +4 more
openaire   +2 more sources

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillmann, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano   +25 more
wiley   +1 more source