Results 41 to 50 of about 6,786,733 (300)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Efficacy and safety of follitropin delta versus follitropin alpha/beta in infertility treatment: A systematic review and meta‐analysis

open access: yesReproductive Medicine and Biology
Background Follitropin δ may be an alternative to conventional follitropin α/β for controlled ovarian stimulation (COS) within assisted reproductive treatment (ART), but its efficacy and safety remain unknown.
Shinnosuke Komiya   +4 more
doaj   +1 more source

Peer review - Why, when and how

open access: yesInternational Journal of Cardiology Congenital Heart Disease, 2021
Peer review has a key role in ensuring that information published in scientific journals is as truthful, valid and accurate as possible. It relies on the willingness of researchers to give of their valuable time to assess submitted papers, not just to ...
Philip J. Steer, Sabine Ernst
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Increasing the degree of acceptability for chatbots in technical support systems for educational sector by using ML and semantic web

open access: yesAlexandria Engineering Journal
Work on digital transformation is one of the main features of the fourth economic revolution, which tends to benefit from technology in various aspects of life.
Adel A. Bahaddad
doaj   +1 more source

Peer Review of Teaching [PDF]

open access: yes, 2009
Convened by Vice Provost for Faculty and Academic Affairs Arlene Carney, this advisory group was charged specifically with recommending best practices for the peer review of teaching.
University of Minnesota. Peer Review of Teaching Advisory Group
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Correlation Between Helicobacter pylori Infection and Tongue Manifestations: A Meta-analysis

open access: yesDigital Chinese Medicine, 2018
: Objective To analyze the relationship between Helicobacter pylori (H. pylori) infection and the manifestations of the tongue.Methods Without language restrictions, we searched databases including CAJD, CBMdisc, CDFD, CMFD, PubMed, Cochrane, and EMBASE ...
Bo-Nan HOU   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

peer review jurnal tasikmalaya [PDF]

open access: yes, 2019
peer review jurnal ...
Arif Senja Fitrani, M.Kom, Arif
core  

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