Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha +13 more
wiley +1 more source
Prepare medical graduates for residency through near-peer teaching: addressing reciprocal determinants. [PDF]
Chien L +11 more
europepmc +1 more source
Impact of near-peer teaching on medical English learning motivation among medical students and residents. [PDF]
Hoshina Y +5 more
europepmc +1 more source
A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng +13 more
wiley +1 more source
Cooking with the curriculum: expanding nutrition knowledge in medical education through a longitudinal, peer teaching, culinary medicine model. [PDF]
Tenney A +9 more
europepmc +1 more source
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu +11 more
wiley +1 more source
Near-peer teaching of laparoscopic skills among medical students: a randomised feasibility study. [PDF]
Ho MP +7 more
europepmc +1 more source
Peer Teaching in Undergraduate Medical Education: What are the Learning Outputs for the Student-Teachers? A Systematic Review. [PDF]
Tanveer MA +7 more
europepmc +1 more source
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng +10 more
wiley +1 more source
Education Research: Case-Based and Near-Peer Teaching on Functional Neurologic Disorder in the Neurology Clerkship: A Cross-Site Comparative Pilot Study. [PDF]
Viola M +3 more
europepmc +1 more source

