Results 121 to 130 of about 179,604 (239)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

From host's descriptions to guests' reviews: Semantic similarities

open access: yesAnnals of Tourism Research Empirical Insights
This study investigates the semantic alignment between Airbnb property descriptions and guest reviews. Word2Vec embeddings and affinity propagation clustering are used to identify granular semantic concepts, enabling a detailed comparison of the two text
Mariana Cavique   +3 more
doaj   +1 more source

Collaboration and the Net generation: The changing characteristics of first year university students [PDF]

open access: yes, 2009
This paper reports on the first phase of research that investigates the Net generation entering university. The paper focuses on claims about the Net generation’s relationship to collaboration and cooperation and the ways that this relationship is ...
Jones, Chris, Ramanau, Ruslan
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Teenage parent supported housing pilot evaluation [PDF]

open access: yes, 2010
Johnsen, Sarah, Quilgars, Deborah
core   +1 more source

Fulfilling Lives: Supporting people with multiple needs, Evaluation Report, Year 1 [PDF]

open access: yes, 2015
This report is prepared for the Big Lottery Fund (the Fund) by the national evaluationteam and provides emerging findings and lessons learned from the first year of thenational evaluation of the Fulfilling Lives: Supporting people with multiple ...
Hayley Lamb   +4 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

‘AIRBNB’ in Western Australia: New Issues for Policy Makers Arising From a ‘Disruptive Innovatation\u27 [PDF]

open access: yes, 2017
The short terms rental market, colloquially referred to as ‘Airbnb’ accommodation, has proliferated the Australian (and international) accommodation market.
De Villiers, Bertus
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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