Results 61 to 70 of about 850,416 (262)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Leadership in Peer Group Mentoring

open access: yesInternational Journal of Evidence Based Coaching and Mentoring
In traditional one-to-one mentoring relationships, the mentor is typically perceived as the leader and the mentee serves as a follower. In peer group mentoring experiences, traditional notions of top-down leadership and hierarchical decision-making are ...
Jonathan Kroll, Regina M. O’Neill
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Association between serial changes in serum C-reactive protein levels and mortality among patients with pleural empyema: a database research

open access: yesBMC Pulmonary Medicine
Background Although previous studies have evaluated C-reactive protein (CRP) as a diagnostic marker for pleural empyema, the prognostic value of baseline and serial CRP measurements has not been adequately assessed.
Akihiro Shiroshita   +4 more
doaj   +1 more source

Pelajar Sehat (Healthy Student) Melalui Upaya Pengembangan Sekolah Peduli Kesehatan

open access: yesMadaniya
Perubahan pola kebiasaan (lifestyle) pada kehidupan masyarakat yang berdampak pada kesehatan, termasuk kesehatan anak usia sekolah. Terganggunya kesehatan siswa oleh penyakit sangat berhubungan dengan pola hidup sehat yang cenderung terabaikan ...
Muliyadi Muliyadi   +5 more
doaj   +1 more source

HUBUNGAN KELOMPOK TEMAN SEBAYA, STRATEGI KOPING, DAN URUTAN KELAHIRAN DENGAN KECERDASAN SOSIAL PADA MAHASISWI TPB IPB

open access: yesJurnal Ilmu Keluarga dan Konsumen, 2013
The research was to analyze the correlation of relationships of peer group, coping strategy, and  birth order with social intelligence of undergraduate female student.
Amania Farah   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Assessing Evidence Quality for Endovascular Arteriovenous Fistulas

open access: yesKidney Medicine, 2022
Yoshinosuke Shimamura, MD, MPH   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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