Results 91 to 100 of about 2,725,232 (305)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Online Braz J of Nursing 2006 Thanks to Peer Reviewers and Authors

Online Brazilian Journal of Nursing, 2006
The editor thanks the OBJN Reviewers and Authors for their competent service during the year 2006.
Isabel CF da Cruz
doaj  

Peer Review Research Evaluation in Iran: Strengths, Weaknesses and Suggestions. [PDF]

Iran J Public Health, 2021
Eftekhari MB, Ebadifar A, Ghalenoee E, Falahat K.   +3 more
europepmc   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Peer Review in Carnegie Research Libraries

College & Research Libraries, 1998
The review of librarians by their peers is an elemental factor in advancement and continuing appointment. This article reports the results of a survey on structure, support, and expectations in place for peer review of librarians. The authors provide comparisons to previous research and discuss new information on the value placed on individual ...
Leysen, Joan, Black, William
openaire   +4 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Rethinking Resource Allocation in Science

, 2019
US funding agencies alone distribute a yearly total of roughly $65B dollars largely through the process of proposal peer review: scientists compete for project funding by submitting grant proposals which are evaluated by selected panels of peer reviewers.
Bollen, Johan, Carpenter, Stephen, Lubchenco, Jane, Scheffer, Marten   +3 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Making available scientific information in the third millennium: perspectives for the neuroscientific community [PDF]

, 2006
The rules governing the globalised process of sharing scientific information in the research community are rapidly changing. From the 1950s, commercial publishers started owning a large number of scientific journals and consequently the marketable value ...
Alleva, Enrico, Branchi, Igor
core  

Role of Peer Review in Surgical Research

The Annals of African Surgery, 2023
Vincent Kipkorir, Stanley Aruyaru, James Kigera   +2 more
doaj   +1 more source