Results 91 to 100 of about 3,137,448 (307)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Peer Review Research Evaluation in Iran: Strengths, Weaknesses and Suggestions. [PDF]

Iran J Public Health, 2021
Eftekhari MB, Ebadifar A, Ghalenoee E, Falahat K.   +3 more
europepmc   +1 more source

Tools used to assess the quality of peer review reports: a methodological systematic review

BMC Medical Research Methodology, 2019
BackgroundA strong need exists for a validated tool that clearly defines peer review report quality in biomedical research, as it will allow evaluating interventions aimed at improving the peer review process in well-performed trials.
C. Superchi, J. González, I. Solá, E. Cobo, Darko Hren, I. Boutron   +5 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Peer review: what are the OBJN responsabilities?

Online Brazilian Journal of Nursing, 2006
As other scientific journals, the Online braz j of nurs is a vehicle to exchange knowledge and scientific information within the scientific and professional community.
Isabel CF da Cruz
doaj  

Using Cinéma Vérité (Truthful Cinema) to Facilitate Replication and Accountability in Psychological Research

Frontiers in Psychology, 2013
To increase replication and accountability, it is proposed that researchers make audio/video recordings of laboratory protocols using currently available technologies, such as smart-phones.
Jerry eSuls
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Peer Review in Carnegie Research Libraries

College & Research Libraries, 1998
The review of librarians by their peers is an elemental factor in advancement and continuing appointment. This article reports the results of a survey on structure, support, and expectations in place for peer review of librarians. The authors provide comparisons to previous research and discuss new information on the value placed on individual ...
Leysen, Joan, Black, William
openaire   +4 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Role of Peer Review in Surgical Research

The Annals of African Surgery, 2023
Vincent Kipkorir, Stanley Aruyaru, James Kigera   +2 more
doaj   +1 more source