Results 91 to 100 of about 2,877,555 (301)

Life Otherwise at the Sea's Edge

open access: yesOpen Rivers, 2019
As part of a longer project on sea edges and coloniality, this essay studies ways of being that exceed the human, nonhuman, and colonial divide, and that find historical nodes of power and affective density at the boundaries of the Americas oceanic...
Macarena Gómez-Barris
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Role of Peer Review in Surgical Research

open access: yesThe Annals of African Surgery, 2023
Vincent Kipkorir   +2 more
doaj   +1 more source

Peer review: what are the OBJN responsabilities?

open access: yesOnline Brazilian Journal of Nursing, 2006
As other scientific journals, the Online braz j of nurs is a vehicle to exchange knowledge and scientific information within the scientific and professional community.
Isabel CF da Cruz
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Peer review processes risk stifling creativity and limiting opportunities for game-changing scientific discoveries [PDF]

open access: yes, 2017
Today, academics must prepare written proposals describing the research they wish to conduct and submit them to funding agencies for evaluation – a process known as peer review.
Braben, Don, Dowler, Rod
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Making available scientific information in the third millennium: perspectives for the neuroscientific community [PDF]

open access: yes, 2006
The rules governing the globalised process of sharing scientific information in the research community are rapidly changing. From the 1950s, commercial publishers started owning a large number of scientific journals and consequently the marketable value ...
Alleva, Enrico, Branchi, Igor
core  

Anomalies in the peer-review system: A case study of the journal of High Energy Physics

open access: yes, 2016
Peer-review system has long been relied upon for bringing quality research to the notice of the scientific community and also preventing flawed research from entering into the literature.
Ganguly, Niloy   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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