Results 111 to 120 of about 2,889,538 (305)
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
To be SEER 1.0 or not to be SEER 2.0? That is one of a few questions
The intent of this editorial is to share the fears related to the migration to a new version of the OJS/PKP and to highlight the strengths of the OBJN with the use of the OJS.
Isabel CF da Cruz
doaj
Evaluate What Is Claimed to Be Confirmed: Initial Version of a Falsification Assessment Form (FAF)
Scientific claims, and the way they are tested, must be unambiguous and flexibility must be disclosed. Grounded in Popper’s principle of falsification, we suggest the Falsification Assessment Form (FAF).
Michael Höfler +9 more
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
What Every Economist Should Know about the Evaluation of Teaching: A Review of the Literature [PDF]
Decades of research consistently show that student evaluations offer limited information on the effectiveness of teaching in economics. Such methods are at best valid for a relatively small set of factors that correlate with "good instruction." Even ...
Stephen B. DeLoach
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Blogging on peer-reviewed research
One of my main goals in this blog is to help non-scientists (Christian readers in particular) understand science and God's world, by reviewing and explaining recently-published scientific research.
openaire +1 more source
Peer reviewers’ conflicts of interest in biomedical research: scoping review
BackgroundPeer review may improve the quality of research manuscripts and aid in editorial decisions, but reviewers can have conflicts of interest that impact on their recommendations.ObjectivesThe objective was to systematically map and describe the extent and nature of empirical research on peer reviewers’ conflicts of interest in biomedical research.
Christoffer Bruun Korfitsen +5 more
openaire +4 more sources

