Results 91 to 100 of about 58,740,720 (292)

Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis

BMJ Open Diabetes Research & Care, 2022
Yuki Kataoka, Jun Watanabe, Yukiko Okami, Hideki Tsunoda   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Life Otherwise at the Sea's Edge

Open Rivers, 2019
As part of a longer project on sea edges and coloniality, this essay studies ways of being that exceed the human, nonhuman, and colonial divide, and that find historical nodes of power and affective density at the boundaries of the Americas oceanic...
Macarena Gómez-Barris
doaj   +1 more source

A new twist on peer review

eLife, 2018
eLife is conducting a trial in which authors will decide how to respond to the issues raised during peer review.
Mark Patterson, Randy Schekman
doaj   +1 more source

Peer reviewers’ conflicts of interest in biomedical research: scoping review [PDF]

BMJ Evidence-Based Medicine
BackgroundPeer review may improve the quality of research manuscripts and aid in editorial decisions, but reviewers can have conflicts of interest that impact on their recommendations.ObjectivesThe objective was to systematically map and describe the extent and nature of empirical research on peer reviewers’ conflicts of interest in biomedical research.
Christoffer Bruun Korfitsen, Camilla Hansen Nejstgaard, Asbjørn Hróbjartsson, Isabelle Boutron, Lisa Bero, Andreas Lundh   +5 more
openaire   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Social Simulation That 'Peers into Peer Review' [PDF]

This article suggests to view peer review as a social interaction problem and shows reasons for social simulators to investigate it. Although essential for science, peer review is largely understudied and current attempts to reform it are not supported ...
Flaminio Squazzoni, K�roly Tak�cs
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Role of Peer Review in Surgical Research

The Annals of African Surgery, 2023
Vincent Kipkorir, Stanley Aruyaru, James Kigera   +2 more
doaj   +1 more source