Results 91 to 100 of about 280,617 (296)
Focal Randomization: An optimal mechanism for the evaluation of R&D [PDF]
In most countries, governments intervene in the process of R&D by financing a substantial part of it. The mechanism employed for choosing the projects to be financed is a committee composed of experts who evaluate projects in their field of ...
Elise Brezis
core
'Rumours' and clinical trials: a retrospective examination of a paediatric malnutrition study in Zambia, southern Africa. [PDF]
BACKGROUND: Many public health researchers conducting studies in resource-constrained settings have experienced negative 'rumours' about their work; in some cases they have been reported to create serious challenges and derail studies.
Patricia Kingori +14 more
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Empowering peer reviewers to nurture writing skills in peer writers [PDF]
A persistent issue in peer revision is whether peer reviewers have sufficient knowledge to critique the works of peer writers. Supporters of social constructivism believe that learners learn best in collaboration. In the ESL context, student writers, who
Attan, Anie, Anie B Attan
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Purpose This letter briefly reviews ideas about the purpose and benefits of peer review and reaches some idealistic conclusions about the process. Method The author uses both literature review and meditation born of long experience. Results
openaire +4 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source

