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Pegvisomant in acromegaly: Why, when, how
Journal of Endocrinological Investigation, 2007N ...
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Pegvisomant therapy for acromegaly
Expert Review of Endocrinology & Metabolism, 2006Despite traditional, multimodality therapy that consisted of surgery, radiotherapy and medical therapies, many patients with acromegaly could not be adequately treated. Pegvisomant is a novel growth hormone receptor antagonist that became available for the treatment of acromegaly in 2003. This drug is a growth hormone variant that has nine mutations to
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