Results 61 to 70 of about 3,554 (229)

Headache characteristics in acromegaly: Only a secondary disorder?

Headache: The Journal of Head and Face Pain, Volume 65, Issue 5, Page 826-834, May 2025.
Abstract Objective To investigate the characteristics and nature of headache in a population of patients with acromegaly. Background Headache is frequently described by patients with pituitary adenomas. Although it is mainly considered a secondary disorder, it can persist despite effective therapy for pituitary disease. A proper description of headache
Giada Giuliani, Denise Costa, Chiara Pellicano, Patrizia Gargiulo, Camilla Virili, Vittorio Di Piero, Marta Altieri   +6 more
wiley   +1 more source

Diabetes mellitus in acromegaly: prevalence, pathophysiological particulars and treatment strategies

Alʹmanah Kliničeskoj Mediciny, 2023
The prevalence of diabetes mellitus in acromegaly is significantly higher than that in the general population. Carbohydrate metabolism abnormalities often precede other phenotypic manifestations of acromegaly.
Irena A. Ilovayskaya, Gagik R. Galstyan
doaj   +1 more source

Validation of serum IGF-I as a biomarker to monitor the bioactivity of exogenous growth hormone agonists and antagonists in rabbits [PDF]

, 2014
The development of new growth hormone (GH) agonists and growth hormone antagonists (GHAs) requires animal models for pre-clinical testing. Ideally, the effects of treatment are monitored using the same pharmacodynamic marker that is later used in ...
Bannink, Berger, Bidlingmaier, Bielohuby, Bielohuby, Bielohuby, Blum, Clemmons, Clemmons, Costa, Courtland, Cox, Daniel-Carlier, Divisova, Domené, D’Ercole, Festoff, Flisikowska, Friedrich, Friedrich, Fu, Grönbladh, Grønbaek, Hossenlopp, Kargi, Kassem, Katter, Katz, Katznelson, Keller, Key, Kopchick, Kopchick, Laeger, Le Roith, Masyuk, Metzger, Møller, Nason, NCCLS, Petersenn, Pinkert, Péter, Rosskopf, Schiller, Sievers, Thakur, Turner, van der Lely, Veldhuis, Veldhuis, Wallis, Wolf, Zapf, Zhang   +54 more
core   +3 more sources

Identification of Coagulation and Fibrinolysis‐Associated Biomarkers With Implications for Preeclampsia

Genetics Research , Volume 2025, Issue 1, 2025.
Background: Coagulation system abnormalities contribute to clinical manifestations in preeclampsia (PE), but the mechanisms of coagulation and fibrinolysis in PE are unclear. Methods: We utilized the Gene Expression Omnibus (GEO) database to obtain the GSE10588 training set and GSE54618 validation set.
Yujie Liu, Tingting Chen, Cuifang Fan, Irfan Ahmad   +3 more
wiley   +1 more source

Early Lung Function Abnormalities in Acromegaly. [PDF]

, 2015
BACKGROUND: Acromegaly is an insidious disorder caused by a pituitary growth hormone (GH)-secreting adenoma resulting in high circulating levels of GH and insulin-like growth factor I (IGF-I). Respiratory disorders are common complications in acromegaly,
A Giustina, A Troyer De, A. Benfante, A. Ciresi, American Thoracic Society, B Trotman-Dickenson, BD Harrison, C. Giordano, F. Cannizzaro, G Burri, GB Camilo, HM O’Brodovich, JS Brody, LA Frohman, M. Bellia, N. Scichilone, NJ Murrant, NM Siafakas, P Attal, PJ Trainer, PM Donnelly, R Pellegrino, S Melmed, S Melmed, V. Bellia   +24 more
core   +1 more source

Multidisciplinary Management of Pituitary Neuroendocrine Tumors During Pregnancy: Institutional Report

International Journal of Endocrinology, Volume 2025, Issue 1, 2025.
Background: Management of pituitary neuroendocrine tumors (pitNETs) during pregnancy is challenging. Involvement of the multidisciplinary team (MDT) may benefit the collaborative decision‐making. However, this aspect has not been well documented. We provided cases with pitNETs during pregnancy and summarized our experience on the MDT‐guided management.
Zhiyuan Xiao, Xiaopeng Guo, Yong Yao, Jifang Liu, Wei Lian, Kan Deng, Yu Zhang, Xia Zhang, Yuanli Zhao, Yi Zhang, Bing Xing, Huijuan Zhu, Suraiya Saleem   +12 more
wiley   +1 more source

Burden of diabetes mellitus in patients with acromegaly treated with second-line pharmacotherapy in Spain

ClinicoEconomics and Outcomes Research, 2019
Laura Sánchez-Cenizo,1 Javier Aller,2 José Manuel Martínez-Sesmero,3 Nuria Mir,1 Carmen Peral,1 Darío Rubio-Rodríguez,4 Carlos Rubio-Terrés41Medical Department, Pfizer, S.L.U, Madrid, Spain; 2Endocronology ...
Sánchez-Cenizo L, Aller J, Martínez-Sesmero JM, Mir N, Peral C, Rubio-Rodríguez D, Rubio-Terrés C   +6 more
doaj  

A consensus on the diagnosis and treatment of acromegaly complications [PDF]

, 2014
In March 2011, the Acromegaly Consensus Group met to revise and update the guidelines on the diagnosis and treatment of acromegaly complications. The meeting was sponsored by the Pituitary Society and the European Neuroendocrinology Association and ...
Bronstein, M. D., Casanueva, F. F., Chanson, P., Giustina, A., Klibanski, A., Lamberts, S. W., Melmed, S., Strasburger, C. J., Wass, J. A. H.   +8 more
core   +1 more source

The Long‐Term Effects of Postoperative Radiotherapy in Acromegaly: Results From a Single‐Center Acromegaly Registry in Iran

International Journal of Endocrinology, Volume 2025, Issue 1, 2025.
Background Acromegaly is a rare but severe condition characterized by the excessive secretion of growth hormone (GH), leading to various metabolic alterations. Treatment options include surgery, pharmacotherapy, and radiotherapy (RT). RT can control the disease biochemically, either alone or in conjunction with medical therapy.
Farzad Najafipour, Javad Jafarpour, Amir Bahrami, Majid Mobasseri, Mitra Niafar, Mostafa Najafipour, Akbar Aliasgarzadeh, Naser Aghamohammadzadeh, Jalil Houshyar, Vahideh Sadra, Naimeh Mesri Alamdari, Suraiya Saleem   +11 more
wiley   +1 more source

Improved AcroQoL scores in acromegaly after sagittal split ramus osteotomy with Le Fort I osteotomy

Endocrinology, Diabetes & Metabolism Case Reports, 2021
Acromegaly is associated with a low quality of life (QoL), which is partially attributable to appearance. However, appearance changes are only partially reversible with treatments of growth hormone excess. This case study describes a 41-year-old Japanese
Tomomi Taguchi, Sachiko Kimizuka, Koji Takano   +2 more
doaj   +1 more source