Results 151 to 160 of about 33,392 (283)

Delivery of Antisense Oligonucleotides Using the Nano‐Cell Vesicle Technology System (nCVTs) for Targeted Cancer Therapy

Small, EarlyView.
Nano‐Cell Vesicle Technology (nCVTs) integrates cationic lipids with tumor‐homing cell membranes to achieve efficient intracellular transport of antisense oligonucleotides. The system enhances nuclear delivery, minimizes cytotoxicity, and suppresses tumor growth in vivo, establishing nCVTs as a versatile and biocompatible platform for next‐generation ...
Yi Hsuan Ou, Wei Heng Chng, Ram Pravin Kumar Muthuramalingam, Prathyusha Raghunathan, Nichakan Khunkitchai, Choon Keong Lee, Jae Ha Jun, Zi Xiu Ng, Phua Tian Xin, Wei Jiang Goh, Jiong‐Wei Wang, Bertrand Czarny   +11 more
wiley   +1 more source

Polymerization and stability of actin conjugated with polyethylene glycol

Biophysics and Physicobiology
This study aimed to elucidate the impact of polyethylene glycol (PEG) conjugation on protein-protein interactions by investigating the properties of PEG-conjugated actin (PEG-actin).
Masaya Sagara, Kuniyuki Hatori
doaj   +1 more source

Effect of pH on Solubilisation of Practically Insoluble Sorafenib by Classic and Stealth Polyamidoamine (PAMAM) Dendrimers and -cyclodextrin [PDF]

, 2012
This study is the first report of the solubilization of sorafenib (SFB), a water insoluble drug, by polyamidoamine (PAMAM) dendrimers and -cyclodextrin ( -CD). For this study whole generations (G4 and G5) of PAMAM dendrimers have been used. The aqueous
Farvadi, F., Hashemi, F., Tamaddon, A.M., Yousefi, G.H.   +3 more
core  

Enhanced Refractive Index Sensitivity of Linearly Assembled Gold Nanoantennae for Biosensing Applications

Small, EarlyView.
This study presents scalable methods for fabricating linear arrays of gold nanoparticles using template‐assisted self‐assembly. These supracolloidal structures show strong polarization‐dependent plasmonic responses for biosensing. Using antibody detection for Tumor Necrosis Factor‐Alpha (TNF‐α) as a proof‐of‐concept, the assemblies exhibit up to five ...
Taufhik Hossain Tonmoy, Sezer Seçkin, Marisa Hoffmann, Isli Çela, Gyusang Yi, Ahmed Alsadig, Swagato Sarkar, Christian Rossner, Tobias A.F. König, Andreas Fery, Larysa Baraban   +10 more
wiley   +1 more source

A case of accidental Ricin poisoning [PDF]

, 2004
A case report of accidental, mild ricin poisoning by ingestion of ten Castor beans by a 70 year old man. The clinical presentation is followed by a discussion about the toxicity of ricin, its use and misuse and the contrast between the toxicity of pure ...
Cachia, Mario J., Despott, Edward
core  

Solid Phase Pegylation of Hemoglobin

, 2009
Xiaoyan Suo, Chunyang Zheng, Pengzhan Yu, Xiuling Lu, Guanghui Ma, Zhiguo Su   +5 more
openalex   +2 more sources

PEGylation of αα-Hb using succinimidyl propionic acid PEG 5K: Conjugation chemistry and PEG shell structure dictate respectively the oxygen affinity and resuscitation fluid like properties of PEG αα-Hbs [PDF]

, 2014
Fantao Meng, Amy G. Tsai, Marcos Intaglietta, Seetharama A. Acharya   +3 more
openalex   +1 more source

Pegylation [PDF]

, 2020
openaire   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, EarlyView.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention

Molecules
In recent years, the near-infrared (NIR) fluorescence theranostic system has garnered increasing attention for its advantages in the simultaneous diagnosis- and imaging-guided delivery of therapeutic drugs.
Xiaohua Wang, Xiaofei Deng, Lilan Xin, Chune Dong, Guoyuan Hu, Hai-Bing Zhou   +5 more
doaj   +1 more source