Results 231 to 240 of about 31,898 (250)
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Process for protein PEGylation
Journal of Controlled Release, 2014PEGylation is a versatile drug delivery technique that presents a particularly wide range of conjugation chemistry and polymer structure. The conjugated protein can be tuned to specifically meet the needs of the desired application. In the area of drug delivery this typically means to increase the persistency in the human body without affecting the ...
David, Pfister, Massimo, Morbidelli
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Ligand-installed PEGylated bionanosphere
IEE Proceedings - Nanobiotechnology, 2005The synthesis of poly(ethylene glycol)-b-poly(2-N,N-dimethylaminoethylmethacrylate) processing an acetal group at the PEG chain end (acetal-PEGPAMA) is reported. The obtained acetal-PEGPAMA block copolymer was found to reduce tetrachloroauric acid at room temperature to produce gold nanoparticles. The size of these nanoparticles was controllable in the
Y, Nagasaki, K, Kataoka
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International Journal of Peptide and Protein Research, 1995
Conditions have been developed for the site‐specific pegylation (NH2‐terminus, side‐chain and carboxyterminus) of a potent analog of growth hormone‐releasing factor, [Ala15]‐hGRF(1‐29)‐NH2. These pegylated peptides were prepared by solid‐phase peptide synthesis using the Fmoc/tBu strategy, and were fully characterized by analytical HPI.C, amino‐acid ...
A M, Felix, Y A, Lu, R M, Campbell
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Conditions have been developed for the site‐specific pegylation (NH2‐terminus, side‐chain and carboxyterminus) of a potent analog of growth hormone‐releasing factor, [Ala15]‐hGRF(1‐29)‐NH2. These pegylated peptides were prepared by solid‐phase peptide synthesis using the Fmoc/tBu strategy, and were fully characterized by analytical HPI.C, amino‐acid ...
A M, Felix, Y A, Lu, R M, Campbell
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Reviews in gastroenterological disorders, 2002
Interferon therapy for chronic hepatitis C is not a cure, but it is able to decrease the viral load and may decrease the risk of complications (e.g., cirrhosis, liver failure, liver cancer). Pegylation of the interferon increases the amount of time the interferon remains in the body by increasing the size of the interferon molecule. Increasing molecule
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Interferon therapy for chronic hepatitis C is not a cure, but it is able to decrease the viral load and may decrease the risk of complications (e.g., cirrhosis, liver failure, liver cancer). Pegylation of the interferon increases the amount of time the interferon remains in the body by increasing the size of the interferon molecule. Increasing molecule
openaire +1 more source