Results 91 to 100 of about 499,147 (343)
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Generalization and variations of Pellet's theorem for matrix polynomials [PDF]
arXiv, 2012 We derive a generalized matrix version of Pellet's theorem, itself based on a generalized Rouch\'{e} theorem for matrix-valued functions, to generate upper, lower, and internal bounds on the eigenvalues of matrix polynomials. Variations of the theorem are suggested to try and overcome situations where Pellet's theorem cannot be applied.
arxiv
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
New satellite systems for obtaining data for Geographic information systems [PDF]
Acta Montanistica Slovaca, 2006 Galileo will be the European global navigation satellite system, providing a highly accurate and a guaranteed global positioning service under the civilian control.
Miroslav Šimčák
doaj
工程科学学报, 2018 The isothermal oxidation kinetics and mineralogical characteristics of Hongge chromium containing vanadium and titanium magnetite (HCVTM) pellets were investigated.
TANG Wei-dong +3 more
doaj +1 more source
Interface heat transfer between crossing carbon nanotubes, and the thermal conductivity of nanotube pellets [PDF]
arXiv, 2008 We theoretically compute the interface thermal resistance between crossing single walled carbon nanotubes of various chiralities, using an atomistic Green's function approach with semi-empirical potentials. The results are then used to model the thermal conductivity of three dimensional nanotube pellets in vacuum.
arxiv
FEBS Open Bio, EarlyView.We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques +5 more
wiley +1 more source
Post-Thermal Quench Shattered Pellet Injection for small Runaway Electron seed depletion in ITER [PDF]
arXiv, 2020 The possibility of using Shattered Pellet Injection(s) after the Thermal Quench phase of an ITER disruption in order to deplete Runaway Electron (RE) seeds before they can substantially avalanche is studied. Analytical and numerical estimates of the required injection rate for shards to penetrate into the forming RE beam and stop REs are given.
arxiv
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source