Results 81 to 90 of about 823,815 (339)

Assessment of Trends in the Global Wood Pellets Market and Opportunities of the Russian Federation in this Market [PDF]

, 2022
Svetlana Karkhova
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Ultrasound-assisted extraction of itraconazole from pellets: an efficient approach for the recovery of active pharmaceutical compounds from solid dosage forms

Frontiers in Analytical Science
IntroductionItraconazole is a widely used broad-spectrum antifungal drug on a global scale. However, its poor water solubility necessitates the development of advanced formulations for its effective use.
Patricia G. Ferreira, Carolina G. S. Lima, Marcela C. de Moraes, Fernando de C. da Silva, Débora O. Futuro, Vitor F. Ferreira   +5 more
doaj   +1 more source

Comparação entre formas físicas da ração no desempenho de leitões do desmame aos setenta dias de idade Comparison between different shapes of ration in the performance of weaning pigs up to seventy days

Ciência Rural, 1995
Um estudo foi realizado no Departamento de Zootecnia da Universidade Federal de Santa Maria, com o objetivo de avaliar o efeito de três formas físicas de ração sobre o desempenho de leitões, do desmame (28 dias de idade) até 70 dias de idade.
Gerson Guarez Garcia, João Carlos Gauer da Silveira   +1 more
doaj   +1 more source

Local extinctions in the small mammal's assemblages between late Holocene and historical times in Talagapa mountains (Patagonia, Argentina): The role of land use changes [PDF]

, 2016
The aim of this work was to evaluate possible changes in the small mammal composition in the Patagonian arid Extra-Andean steppes between the late Holocene and historical times.
Andrade, Analia, Monjeau, Jorge Adrian
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PELLETS AND PELLETIZATION TECHNIQUES: A CRITICAL REVIEW

International Research Journal of Pharmacy, 2016
In the pharmaceutical industry , pellets can be defined a s small, free - flowing, spherical particulates manufactured by the agglomeration of fine powders or granules of drug substances and excipients using appropriate processing equipment. Pelletization has gained a great interest in recent years due to its vario us advantages over other similar ...
Ratul Deb, Abdul Baquee Ahmed
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Synthesis, Sintering, and Electrical Properties of BaCe0.9−xZrxY0.1O3−δ [PDF]

, 2008
BaCe0.9−xZrxY0.1O3−δ powders were synthesized by a solid-state reaction. Different contents of cerium and zirconium were studied. Pellets were sintered using either conventional sintering in air at 1700◦C or the Spark Plasma Sintering (SPS) technique ...
Bonanos, Nikolaos, Caboche, Gilles, Estournès, Claude, Ricote, Sandrine   +3 more
core   +4 more sources