Results 81 to 90 of about 393,742 (342)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

PELLETING OF SEED

Proceedings of the New Zealand Grassland Association, 1949
The need for clover in pastures is becoming increasingly well recognised and has been adequately dealt with, particularly regarding hill country pastures in the two papers already presented this morning.
H.A. Browning, S.H. Saxby, K.F. Hoy
openaire   +2 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Utilization of wood and bark of fast-growing hardwood species in energy production

Journal of Forest Science, 2018
In this research, the calorific value and ash content of wood and bark of some fast-growing hardwood species, such as tree-of-heaven, (Ailanthus altissima (Miller) Swingle), empress tree (Paulownia tomentosa (Thunberg) Steudel), trembling aspen (Populus ...
Vasiliki KAMPERIDOU, Charalampos LYKIDIS, Panagiotis BARMPOUTIS   +2 more
doaj   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Numerical simulation of the effect of pellet injection on ELMs [PDF]

, 2019
We report on numerical simulation studies of the dynamical behavior of edge localized modes (ELMs) under the influence of repetitive injection of pellets. In our nonlinear 2-fluid model the ELMs are excited by introducing a particle source in the confinement region and a particle sink in the edge region.
arxiv   +1 more source

A PELLET FEEDER FOR THE BIRDS [PDF]

Journal of the Experimental Analysis of Behavior, 1979
An alternative means of delivering food to pigeons in operant conditioning research is described. The feeder allows greater control of the amount of food delivered and reduces the amount of time necessary for the pigeon to collect the food. It is possible to extend the length of experimental sessions due to the reduction of food intake.
openaire   +3 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Pelletization of catalysts supported on activated carbon. A Case Study: clean synthesis of dimethyl carbonate from methanol and CO2

Revista Facultad de Ingeniería Universidad de Antioquia, 2016
The synthesis of Cu-Ni bimetallic catalyst supported on pellets of activated carbon using carboxymethylcellulose (CMC) as a binder is reported. The effect of preparation conditions, such as binder concentration, AC/binder ratio, temperature, and ...
Andrés Felipe Orrego-Romero, Oscar Felipe Árbelaez-Pérez, Felipe Bustamante-Londoño, Aída Luz Villa Holguín   +3 more
doaj   +1 more source

Energy Utilization of Spent Coffee Grounds in the Form of Pellets

Energies, 2020
Nowadays it is important to limit the use and combustion of fossil fuels such as oil and coal. There is a need to create environmentally acceptable projects that can reduce or even stop greenhouse gas emissions.
Radovan Nosek, Maw Maw Tun, Dagmar Juchelkova   +2 more
doaj   +1 more source