Results 11 to 20 of about 18,796 (270)

Upregulation of FAM83F by c-Myc promotes cervical cancer growth and aerobic glycolysis via Wnt/β-catenin signaling activation

open access: yesCell Death and Disease, 2023
Cervical cancer (CC) seriously affects women’s health. Therefore, elucidation of the exact mechanisms and identification of novel therapeutic targets are urgently needed.
Changlin Zhang   +12 more
doaj   +1 more source

Dysregulation and implications of N6-methyladenosine modification in renal cell carcinoma

open access: yesCurrent Urology, 2023
. Increasing evidence indicates that N6-methyladenosine (m6A) methylation modification serves important functions in biological metabolism. Dysregulation of m6A regulators is related to the progression of different malignancies, including renal cell ...
Yaohai Wu   +3 more
doaj   +1 more source

MicroRNA-regulated transcriptome analysis identifies four major subtypes with prognostic and therapeutic implications in prostate cancer

open access: yesComputational and Structural Biotechnology Journal, 2021
MicroRNA (miRNA) deregulation plays a critical role in the heterogeneous development of prostate cancer (PCa) by tuning mRNA levels. Herein, we aimed to characterize the molecular features of PCa by clustering the miRNA-regulated transcriptome with non ...
Bing-Biao Lin   +10 more
doaj   +1 more source

Knowledge level of pelvic floor and pelvic floor disorders according to and related disorders according to gender and education levels [PDF]

open access: yes, 2023
Pelvic floor disorders, their management and protective educational programs have become popular in recent years. The aim of this study is to determine the level of knowledge about pelvic floor health according to gender and education levels.
YILDIZ ÖZER, AYSEL
core   +3 more sources

Association of cigarette smoking habits with the risk of prostate cancer: a systematic review and meta-analysis

open access: yesBMC Public Health, 2023
Background Association of cigarette smoking habits with the risk of prostate cancer is still a matter of debate. This systematic review and meta-analysis aimed to assess the association between cigarette smoking and prostate cancer risk.
Xiangwei Yang   +5 more
doaj   +1 more source

Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1–to–M2 transformation

open access: yesFrontiers in Physiology, 2023
Background: With an increasing number of patients experiencing infertility due to chronic salpingitis after Chlamydia trachomatis (CT) infection, there is an unmet need for tissue repair or regeneration therapies.
Changlin Zhang   +15 more
doaj   +1 more source

Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study [PDF]

open access: yes, 2022
Introduction: Pelvic organ prolapse affects around 40% of women aged over 50 years. A multicentre parallel group randomised trial (the Pelvic Organ Prolapse PhysiotherapY (POPPY) trial) demonstrated pelvic floor muscle training (PFMT) was effective in ...
Mason, Helen   +7 more
core   +1 more source

Characterizing the Prevalence of Pelvic Floor Disorders in Males and Females With Lower Limb Amputation: Initial Study Findings. [PDF]

open access: yesJ Womens Pelvic Health Phys Ther
Purpose: Investigate the prevalence of pelvic floor disorder symptoms in males and females with unilateral lower limb amputation. Methods: This was a cross-sectional survey-based study.
Clemens S   +5 more
europepmc   +2 more sources

Biofeedback for Pelvic Floor Disorders

open access: yesClinics in Colon and Rectal Surgery, 2020
AbstractDefecatory disorders can include structural, neurological, and functional disorders in addition to concomitant symptoms of fecal incontinence, functional anorectal pain, and pelvic floor dyssynergia. These disorders greatly affect quality of life and healthcare costs. Treatment for pelvic floor disorders can include medications, botulinum toxin,
Melissa, Hite, Thomas, Curran
openaire   +3 more sources

Learning with the Amerindians: the evaluation of pelvic floor disorders among indigenous women who live in the Xingu Indian Park,Brazil [PDF]

open access: yes, 2008
Objective: to evaluate the pelvic floor muscles and the incidence of pelvic organ prolapse among indigenous women who live in Xingu Indian Park, Mato Grosso, Brazil. Methods: observational study with 377 indigenous women, mean age 31+/-15 years,
Marair Gracio Ferreira Sartori   +3 more
core   +2 more sources

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