Results 11 to 20 of about 16,979 (240)

Upregulation of FAM83F by c-Myc promotes cervical cancer growth and aerobic glycolysis via Wnt/β-catenin signaling activation

open access: yesCell Death and Disease, 2023
Cervical cancer (CC) seriously affects women’s health. Therefore, elucidation of the exact mechanisms and identification of novel therapeutic targets are urgently needed.
Changlin Zhang   +12 more
doaj   +1 more source

Dysregulation and implications of N6-methyladenosine modification in renal cell carcinoma

open access: yesCurrent Urology, 2023
. Increasing evidence indicates that N6-methyladenosine (m6A) methylation modification serves important functions in biological metabolism. Dysregulation of m6A regulators is related to the progression of different malignancies, including renal cell ...
Yaohai Wu   +3 more
doaj   +1 more source

MicroRNA-regulated transcriptome analysis identifies four major subtypes with prognostic and therapeutic implications in prostate cancer

open access: yesComputational and Structural Biotechnology Journal, 2021
MicroRNA (miRNA) deregulation plays a critical role in the heterogeneous development of prostate cancer (PCa) by tuning mRNA levels. Herein, we aimed to characterize the molecular features of PCa by clustering the miRNA-regulated transcriptome with non ...
Bing-Biao Lin   +10 more
doaj   +1 more source

Association of cigarette smoking habits with the risk of prostate cancer: a systematic review and meta-analysis

open access: yesBMC Public Health, 2023
Background Association of cigarette smoking habits with the risk of prostate cancer is still a matter of debate. This systematic review and meta-analysis aimed to assess the association between cigarette smoking and prostate cancer risk.
Xiangwei Yang   +5 more
doaj   +1 more source

Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1–to–M2 transformation

open access: yesFrontiers in Physiology, 2023
Background: With an increasing number of patients experiencing infertility due to chronic salpingitis after Chlamydia trachomatis (CT) infection, there is an unmet need for tissue repair or regeneration therapies.
Changlin Zhang   +15 more
doaj   +1 more source

Biofeedback for Pelvic Floor Disorders

open access: yesClinics in Colon and Rectal Surgery, 2020
AbstractDefecatory disorders can include structural, neurological, and functional disorders in addition to concomitant symptoms of fecal incontinence, functional anorectal pain, and pelvic floor dyssynergia. These disorders greatly affect quality of life and healthcare costs. Treatment for pelvic floor disorders can include medications, botulinum toxin,
Melissa, Hite, Thomas, Curran
openaire   +3 more sources

Comparison of two methods for evaluating lower urinary tract symptoms in cervical cancer patients following radical hysterectomy

open access: yesGynecology and Obstetrics Clinical Medicine, 2021
Objective: To compare the degree of agreement and consistency of urodynamic studies (UDS) with low urinary tract symptoms (LUTS) questionnaires for evaluating LUTS in cervical cancer patients following radical hysterectomy (RH) and pelvic lymphadenectomy.
Fang An   +17 more
doaj   +1 more source

Efficacy and safety of Androgen Deprivation Therapy (ADT) combined with modified docetaxel chemotherapy versus ADT combined with standard docetaxel chemotherapy in patients with metastatic castration-resistant prostate cancer: study protocol for a multicentre prospective randomized controlled trial

open access: yesBMC Cancer, 2022
Background Androgen deprivation therapy (ADT) combined with docetaxel chemotherapy is the standard treatment for metastatic castration-resistant prostate cancer (mCRPC) patients.
Xiangwei Yang   +7 more
doaj   +1 more source

Long-Term Effect of Early Post-operative Transcutaneous Electrical Stimulation on Voiding Function After Radical Hysterectomy: A Multicenter, Randomized, Controlled Trial

open access: yesFrontiers in Medicine, 2021
Introduction: Post-radical-hysterectomy (RH) patients suffer from a series of problems resulting from neurovascular injury, such as bladder dysfunction, which reduce their quality of life.
Xiao-wei Li   +23 more
doaj   +1 more source

Pathogenesis of dyspareunia associated with pelvic floor dysfunction: A review [PDF]

open access: yesГинекология, 2023
Dyspareunia is a condition associated with a wide range of disorders. Pelvic floor dysfunction, manifesting as a myofascial syndrome or pelvic floor muscle hypertonia, may predict dyspareunia in women in different age groups.
Elena S. Silantyeva   +3 more
doaj   +1 more source

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