Results 11 to 20 of about 40,026 (289)

Dysregulation and implications of N6-methyladenosine modification in renal cell carcinoma

Current Urology, 2023
. Increasing evidence indicates that N6-methyladenosine (m6A) methylation modification serves important functions in biological metabolism. Dysregulation of m6A regulators is related to the progression of different malignancies, including renal cell ...
Yaohai Wu, Shiqiang Zhang, Chujie Chen, Jun Pang   +3 more
doaj   +1 more source

MicroRNA-regulated transcriptome analysis identifies four major subtypes with prognostic and therapeutic implications in prostate cancer

Computational and Structural Biotechnology Journal, 2021
MicroRNA (miRNA) deregulation plays a critical role in the heterogeneous development of prostate cancer (PCa) by tuning mRNA levels. Herein, we aimed to characterize the molecular features of PCa by clustering the miRNA-regulated transcriptome with non ...
Bing-Biao Lin, Han-Qi Lei, Hai-Yun Xiong, Xing Fu, Fu Shi, Xiang-Wei Yang, Ya-Fei Yang, Guo-Long Liao, Yu-Peng Feng, Dong-Gen Jiang, Jun Pang   +10 more
doaj   +1 more source

Association of cigarette smoking habits with the risk of prostate cancer: a systematic review and meta-analysis

BMC Public Health, 2023
Background Association of cigarette smoking habits with the risk of prostate cancer is still a matter of debate. This systematic review and meta-analysis aimed to assess the association between cigarette smoking and prostate cancer risk.
Xiangwei Yang, Hong Chen, Shiqiang Zhang, Xianju Chen, Yiyu Sheng, Jun Pang   +5 more
doaj   +1 more source

Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1–to–M2 transformation

Frontiers in Physiology, 2023
Background: With an increasing number of patients experiencing infertility due to chronic salpingitis after Chlamydia trachomatis (CT) infection, there is an unmet need for tissue repair or regeneration therapies.
Changlin Zhang, Wei Liao, Weizhao Li, Mengxiong Li, Xiaoyu Xu, Haohui Sun, Yaohua Xue, Lixiang Liu, Jiehong Qiu, Chi Zhang, Xunzhi Zhang, Juntong Ye, Jingran Du, David Y. B. Deng, Wuguo Deng, Tian Li   +15 more
doaj   +1 more source

Pelvic floor disorders in gynecological malignancies. An overlooked problem? [PDF]

, 2018
Cervical, endometrial, ovarian, vulvar, and vaginal cancers affect women of a broad age spectrum. Many of these women are still sexually active when their cancer is diagnosed.
Bodean, Oana M., Cirstoiu, Monica, Diaconu, Camelia C., Marcu, Radu D., Munteanu, Octavian, Socea, Bogdan, Spinu, Dan A., Taus, Nicoleta   +7 more
core   +6 more sources

Comparison of two methods for evaluating lower urinary tract symptoms in cervical cancer patients following radical hysterectomy

Gynecology and Obstetrics Clinical Medicine, 2021
Objective: To compare the degree of agreement and consistency of urodynamic studies (UDS) with low urinary tract symptoms (LUTS) questionnaires for evaluating LUTS in cervical cancer patients following radical hysterectomy (RH) and pelvic lymphadenectomy.
Fang An, Sha Wang, Zhiqi Wang, Lingying Wu, Qiubo Lv, Aiming Lv, Hongwu Wen, Jinsong Han, Yumei Wu, Yunong Gao, Qing Liu, Sumei Wang, Hongxia Li, Luwen Wang, Yanlong Wang, Ruifang Wu, Huan Li, Xiuli Sun   +17 more
doaj   +1 more source

Bio-mechanical risk factors for uterine prolapse among women living in the hills of west Nepal: A case-control study. [PDF]

, 2020
OBJECTIVE:To investigate whether heavy load carrying, wearing a patuka, and body position at work are risk factors for uterine prolapse among Nepali women.
Bates, Michael N, Devkota, Hridaya Raj, Ghimire, Dirgha J, Harris, Carisa, Prata, Ndola, Sijali, Tula Ram   +5 more
core   +2 more sources

Efficacy and safety of Androgen Deprivation Therapy (ADT) combined with modified docetaxel chemotherapy versus ADT combined with standard docetaxel chemotherapy in patients with metastatic castration-resistant prostate cancer: study protocol for a multicentre prospective randomized controlled trial

BMC Cancer, 2022
Background Androgen deprivation therapy (ADT) combined with docetaxel chemotherapy is the standard treatment for metastatic castration-resistant prostate cancer (mCRPC) patients.
Xiangwei Yang, Hong Chen, Duanya Xu, Xianju Chen, Yamei Li, Jun Tian, Dongwen Wang, Jun Pang   +7 more
doaj   +1 more source

Long-Term Effect of Early Post-operative Transcutaneous Electrical Stimulation on Voiding Function After Radical Hysterectomy: A Multicenter, Randomized, Controlled Trial

Frontiers in Medicine, 2021
Introduction: Post-radical-hysterectomy (RH) patients suffer from a series of problems resulting from neurovascular injury, such as bladder dysfunction, which reduce their quality of life.
Xiao-wei Li, Xiao-wei Li, Lei Gao, Lei Gao, Qing Wang, Qing Wang, Qiu-bo Lv, Zhi-jun Xia, Hong-wu Wen, Jin-song Han, Yu-mei Wu, Su-mei Wang, Qing Liu, Huan Li, Hai-bo Wang, Yi Li, Shi-yan Wang, Shi-yan Wang, Zhi-qi Wang, Zhi-qi Wang, Xiu-li Sun, Xiu-li Sun, Jian-liu Wang, Jian-liu Wang   +23 more
doaj   +1 more source

Do the digestive tract symptoms in eating disorder patients represent functional gastrointestinal disorders? [PDF]

, 2013
BACKGROUND: Gastrointestinal (GI) symptoms are common in patients with eating disorders. The aim of this study was to determine, using factor analysis, whether these GI symptom factors (clusters) in eating disorder patients hold true to the Rome II ...
John E Kellow, Suzanne Abraham
core   +1 more source