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Lancet, The, 2019
Pemphigus consists of a group of rare and severe autoimmune blistering diseases mediated by pathogenic autoantibodies mainly directed against two desmosomal adhesion proteins, desmoglein (Dsg)1 and Dsg3 (also known as DG1 and DG3), which are present in the skin and surface-close mucosae.
Enno Schmidt, Pascal Joly
exaly +5 more sources
Pemphigus consists of a group of rare and severe autoimmune blistering diseases mediated by pathogenic autoantibodies mainly directed against two desmosomal adhesion proteins, desmoglein (Dsg)1 and Dsg3 (also known as DG1 and DG3), which are present in the skin and surface-close mucosae.
Enno Schmidt, Pascal Joly
exaly +5 more sources
Dental Clinics of North America, 2005
Pemphigus is an umbrella term for more than 10 different epidermal disease types and subtypes currently classified under this name. Characteristic for pemphigus are the presence of autoantibodies against epidermal cell adhesion structures (desmosomes), leading to a breakdown of cutaneous and mucosal barriers.
Jean-Claude, Bystryn +1 more
openaire +5 more sources
Pemphigus is an umbrella term for more than 10 different epidermal disease types and subtypes currently classified under this name. Characteristic for pemphigus are the presence of autoantibodies against epidermal cell adhesion structures (desmosomes), leading to a breakdown of cutaneous and mucosal barriers.
Jean-Claude, Bystryn +1 more
openaire +5 more sources
Journal of the European Academy of Dermatology and Venereology, 2008
AbstractPemphigus refers to a group of potentially life‐threatening autoimmune diseases of the skin and mucous membranes, characterized by the formation of blisters and erosions of the skin. An autoimmune process, directed against keratinocyte desmosomal cadherins, interferes with the adhesive function of these molecules. This results in the separation
D, Ioannides +2 more
openaire +2 more sources
AbstractPemphigus refers to a group of potentially life‐threatening autoimmune diseases of the skin and mucous membranes, characterized by the formation of blisters and erosions of the skin. An autoimmune process, directed against keratinocyte desmosomal cadherins, interferes with the adhesive function of these molecules. This results in the separation
D, Ioannides +2 more
openaire +2 more sources
La Presse Médicale, 2010
Pemphigus is a rare autoimmune blistering disorder involving the skin and mucosae. Three types of pemphigus have been described, including pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. Diagnosis of the type of pemphigus is made by the combination of clinical features, histological and direct immunofluorescence findings, and ...
Hélène, Lapeyre-Liénard, Pascal, Joly
openaire +2 more sources
Pemphigus is a rare autoimmune blistering disorder involving the skin and mucosae. Three types of pemphigus have been described, including pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. Diagnosis of the type of pemphigus is made by the combination of clinical features, histological and direct immunofluorescence findings, and ...
Hélène, Lapeyre-Liénard, Pascal, Joly
openaire +2 more sources
Clinical Pharmacology & Therapeutics, 1974
Pemphigus is a disease affecting principally the epidermis and mucous membranes of man. The disease is quite distinctive clinically, histologically, and immunologically. It is of importance to discuss in this Workshop because of two interesting facets: the role played in pathogenesis by circulating autoantibodies and the huge doses of corticosteroids ...
openaire +2 more sources
Pemphigus is a disease affecting principally the epidermis and mucous membranes of man. The disease is quite distinctive clinically, histologically, and immunologically. It is of importance to discuss in this Workshop because of two interesting facets: the role played in pathogenesis by circulating autoantibodies and the huge doses of corticosteroids ...
openaire +2 more sources
Pemphigus Vulgaris and Paraneoplastic Pemphigus
Oral and Maxillofacial Surgery Clinics of North America, 2008The history, epidemiology, pathophysiology, clinical presentation, diagnostic work-up, histopathology, and treatment of PV and PNP have been presented. These life-threatening, autoimmune, mucocutaneous bullous conditions may be encountered first by oral health providers and, therefore, deserve keen understanding and attention by the oral and ...
Wendell A, Edgin +2 more
openaire +2 more sources