Ca2+ signalling is critical for autoantibody‐induced blistering of human epidermis in pemphigus *
British Journal of Dermatology, 2021 Pemphigus is a severe bullous autoimmune skin disease. Pemphigus foliaceus (PF) is characterized by antidesmoglein (Dsg) 1 IgG causing epidermal blistering; mucosal pemphigus vulgaris (mPV) by anti‐Dsg3 IgG inducing erosions in the mucosa; and ...
T. Schmitt +10 more
semanticscholar +1 more source
Clonal mixing in the soldier-producing aphid Pemphigus spyrothecae (Hemiptera: Aphididae) [PDF]
, 2002 Illuminating the genetic relationships within soldier-producing aphid colonies is an essential element of any attempt to explain the evolution of the altruistic soldier caste.
Amos +4 more
core +2 more sources
Clinics, 2011 OBJECTIVES: To evaluate the reactivity of indirect immunofluorescence using rat bladder epithelium as a substrate in patients with pemphigus foliaceus and pemphigus vulgaris from the Department of Dermatology, University of São Paulo Medical School ...
Damaris G. Ortolan +6 more
doaj +1 more source
Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Pemphigus Vulgaris and Bullous Pemphigoid: Update on Diagnosis and Treatment
Dermatology Practical & Conceptual, 2020 Autoimmune bullous disorders are a heterogeneous spectrum of skin disorders characterized by the production of autoantibodies against adhesion molecules of the skin. The 2 major groups of diseases are “pemphigus diseases” and “autoimmune bullous diseases
V. Di Lernia +3 more
semanticscholar +1 more source
Keratinocyte Binding Assay Identifies Anti-Desmosomal Pemphigus Antibodies Where Other Tests Are Negative [PDF]
, 2018 The serological diagnosis of pemphigus relies on the detection of IgG autoantibodies directed against the epithelial cell surface by indirect immunofluorescence (IIF) on monkey esophagus and against desmoglein 1 (Dsg1) and Dsg3 by ELISA.
Diercks, Gilles F. H. +4 more
core +5 more sources
Usefulness of miRNA-338-3p in the diagnosis of pemphigus and its correlation with disease severity [PDF]
PeerJ, 2018 Background Pemphigus is a common life-threatening, autoimmune bullous disease effecting both cutaneous and mucous membranes. Previous diagnosis of pemphigus is based on clinical presentations, histopathology, immunofluorescence and enzyme-linked ...
Naiyu Lin +4 more
doaj +2 more sources
Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. [PDF]
, 2018 Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous ...
Damotte, Vincent +2 more
core +1 more source
Pemphigus: Current and Future Therapeutic Strategies
Frontiers in Immunology, 2019 Pemphigus encompasses a heterogeneous group of autoimmune blistering diseases, which affect both mucous membranes and the skin. The disease usually runs a chronic-relapsing course, with a potentially devastating impact on the patients' quality of life ...
D. Didona, R. Maglie, R. Eming, M. Hertl
semanticscholar +1 more source
Evaluation of cases of pemphigus vulgaris and pemphigus foliaceus from a reference service in Pará state, Brazil [PDF]
Anais Brasileiros de Dermatologia, 2014 BACKGROUND: Pemphigusis a bullous, rare and chronic autoimmune disease. There are two major forms of pemphigus: vulgaris and foliaceus. Epidemiological data and clinical outcome in patients diagnosed in the Brazilian Amazon states are still rare ...
Carla Andréa Avelar Pires +5 more
doaj +1 more source