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Current status and considerations on the diagnosis and treatment of pemphigus in China [PDF]
Zhenduanxue lilun yu shijian, 2023 Pemphigus is a rare autoimmune bullous disease with chronic and high rates of relapse. The diagnosis of pemphigus in China has following problems: first, the difficulty of early diagnosis commonly causes missed diagnosis or misdiagnosis with eczema ...
PAN Meng, WANG Jingying
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The value of trichoscopy in the differential diagnosis of scalp lesions in pemphigus vulgaris and pemphigus foliaceus [PDF]
Anais Brasileiros de Dermatologia, 2014 BACKGROUND: Trichoscopy is becoming increasingly popular in diagnosing hair and scalp diseases. Scalp involvement in pemphigus is common. The scalp may be the first or only site of clinical manifestation of the disease.
Marta Sar-Pomian +3 more
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Clinical, Histopathologic, and Immunohistochemical Features of Patients with IgG/IgA Pemphigus
Biomedicines, 2022 Pemphigus is an autoantibody-mediated blistering disease. In addition to conventional pemphigus vulgaris and pemphigus foliaceus, several other types have been reported. Among them, IgG/IgA pemphigus is less well defined and seldom reported.
Yung-Tsu Cho +4 more
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Nature Reviews Disease Primers, 2017 Pemphigus is a group of IgG-mediated autoimmune diseases of stratified squamous epithelia, such as the skin and oral mucosa, in which acantholysis (the loss of cell adhesion) causes blisters and erosions. Pemphigus has three major subtypes: pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus.
Michael, Kasperkiewicz +6 more
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The pathogenesis of pemphigus: controversy versus complexity. [PDF]
, 2017 Life is highly complex and, as quantum physics would predict, follows the rule of "everything is possible with varying probabilities". Accordingly, science may be sometimes as confusing as political debates, where the same matter is addressed in ...
Müller, Eliane Jasmine +2 more
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Post-Pemphigus Acanthomata Presenting as an Isolated, Hyperkeratotic Plaque
Dermatopathology, 2023 Post-pemphigus acanthomas have been rarely discussed in the literature. A prior case series identified 47 cases of pemphigus vulgaris and 5 cases of pemphigus foliaceus, out of which 13 developed acanthomata as a part of the healing process. Additionally,
Rachita Pandya +4 more
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Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
, 2003 Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +19 more
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Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion. [PDF]
, 2013 Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1-4 and desmocollin (Dsc) 1-3 build the adhesive core of ...
Bettina Kempf +17 more
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, 2022 Pemphigus is a group of chronic mucocutaneous blistering diseases caused by autoantibodies directed against the desmosomal cadherins desmoglein 1 and/or desmoglein 3 (Table 8.1). Pemphigus can be divided into two major forms, pemphigus foliaceus (PF) and
Barbara Horváth +6 more
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The human skin organ culture model as an optimal complementary tool for murine pemphigus models. [PDF]
, 2023 Pemphigus is a severe autoimmune bullous disease of the skin and/or mucous membranes caused by autoantibodies that mainly target the adhesion proteins desmoglein (Dsg) 3 and/or Dsg1.
Hammers, Christoph M +13 more
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