Results 41 to 50 of about 2,531 (169)

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

JEADV Clinical Practice, Volume 5, Issue 2, Page 415-424, June 2026.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri, Marta Dechant, Tilo Biedermann   +2 more
wiley   +1 more source

Ultrastructural skin alterations of healthy subjects with anti-desmoglein 1 antibodies in endemic areas to pemphigus foliaceus: A case series

Journal of Translational Autoimmunity, 2023
Background: Endemic pemphigus foliaceus and endemic pemphigus vulgaris are autoimmune dermatologic disorders endemic to the Peruvian Amazon. Objective: To determine the ultrastructural skin alterations of three healthy subjects with anti DSG-1 antibodies
Willy Ramos, Nancy Rojas, Alex G. Ortega-Loayza, Mercedes Tello, Gerardo Jiménez, Nicolás Cuba-Cáceres, Gerardo Ronceros, Jhony A. De La Cruz-Vargas, Víctor Juan Vera-Ponce, Nadia Guerrero, Ericson L. Gutierrez   +10 more
doaj   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Treatment of pemphigus vulgaris and pemphigus foliaceus: experience with 71 patients over a 20 year period Tratamento do pênfigo vulgar e pênfigo foliáceo: experiência com 71 pacientes no período de 20 anos

Revista do Instituto de Medicina Tropical de São Paulo, 2001
Forty one cases of pemphigus vulgaris and thirty cases of pemphigus foliaceus were investigated at Hospital Universitário Clementino Fraga Filho from 1978 to 1999.
Nurimar C. FERNANDES, Mauricio PEREZ
doaj   +1 more source

Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT Mitogen‐activated protein kinases (MAPKs) are intracellular signalling proteins that modulate several cellular processes, such as proliferation, cytokine production and survival. Like humans, dogs may exhibit changes in MAPK signalling under pathological conditions.
Francini Neves Ribeiro, Fernanda Nazaré Morgado, Renato Porrozzi   +2 more
wiley   +1 more source

Adjuvant therapy of severe and/or refractory bullous pemphigoid with immunoadsorption – A prospective monocenter pilot study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 472-479, April 2026.
Summary Background and Objectives Bullous pemphigoid (BP) is the most common autoimmune blistering disease in the Western world. While remission is achieved in the majority of BP patients by long‐term use of corticosteroids with or without immunomodulants/immunosuppressants, national and international guidelines recommend adjuvant immunoadsorption (IA)
Maike M. Holtsche, Nina van Beek, Christoph M. Hammers, Artem Vorobyev, Michael Kasperkiewicz, Nina Schumacher, Philip Muck, Enno Schmidt   +7 more
wiley   +1 more source

The Transition from Pemphigus Foliaceus to Pemphigus Vegetans—An Intriguing Phenomenon within the Spectrum of Autoimmune Blistering Diseases: A Case Report

Dermato
Pemphigus vegetans and pemphigus foliaceus are rare autoimmune blistering diseases characterized by the disruption of desmosomal adhesion proteins, particularly desmoglein 3 and desmoglein 1.
Olguța Anca Orzan, Liliana Gabriela Popa, Iulia Badiu, Ana Ion, Călin Giurcăneanu, Beatrice Bălăceanu-Gurău, Irina Tudose   +6 more
doaj   +1 more source

Adjuvante Therapie des schweren und/oder refraktären bullösen Pemphigoids mit Immunadsorption – eine prospektive monozentrische Pilotstudie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 472-481, April 2026.
Zusammenfassung Hintergrund und Zielsetzung Das bullöse Pemphigoid (BP) ist die häufigste blasenbildende Autoimmunerkrankung in der westlichen Welt. Während die Mehrheit der Patienten mit BP durch die langfristige Anwendung von Kortikosteroiden mit oder ohne Immunmodulatoren/Immunsuppressiva Remissionen erreicht, empfehlen nationale und internationale ...
Maike M. Holtsche, Nina van Beek, Christoph M. Hammers, Artem Vorobyev, Michael Kasperkiewicz, Nina Schumacher, Philip Muck, Enno Schmidt   +7 more
wiley   +1 more source

Pemphigus Foliaceus—Repeated Treatment With Rituximab 7 Years After Initial Response: A Case Report

Frontiers in Medicine, 2018
Pemphigus foliaceus is an autoimmune skin disease mediated by autoantibodies directed against desmoglein-1 located in the upper epidermal layer. Rituximab, a monoclonal anit-CD20 antibody depleting b-cells, offers an effective treatment possibility for ...
Magdalena Kraft, Margitta Worm
doaj   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Journal of Oral Pathology &Medicine, Volume 55, Issue 4, Page 391-418, April 2026.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini, Gioele Gioco, Michele Davide Mignogna, Stefania Leuci, Francesco Scilla, Davide Gentile, Cosimo Rupe, Enrico Russo, Anna Schiavelli, Carlo Lajolo   +9 more
wiley   +1 more source