Results 61 to 70 of about 2,531 (169)

JAK Inhibitors as a Novel Approach to Autoimmune Bullous Diseases: A Review

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Autoimmune bullous diseases (AIBDs) are a group of chronic disorders characterized by blister formation resulting from abnormal immune responses. Janus kinase (JAK) inhibitors have emerged as promising therapeutic agents for AIBDs. This review discusses the use of JAK inhibitors—such as upadacitinib, baricitinib, tofacitinib, and abrocitinib, among ...
Olga Olisova   +9 more
wiley   +1 more source

Childhood pemphigus

open access: yesIndian Journal of Dermatology, 2006
Childhood pemphigus is a rare diasease and comprises only a minority of immunobullous diseases seen in children. Almost all variants of pemphigus in childhood have been described in literature.
De Dipankar, Kanwar Amrinder
doaj  

CTLA4 CT60 gene polymorphism is not associated with differential susceptibility to pemphigus foliaceus

open access: yesGenetics and Molecular Biology, 2010
Pemphigus foliaceus is an organ-specific autoimmune disease characterized by autoantibodies against the extracellular region of desmoglein 1, a protein that mediates intercellular adhesion in desmosomes.
Márcia Regina Pincerati   +2 more
doaj  

Analysis of human leukocyte antigen genotypes in pemphigus with antidesmoglein antibody profile shift

open access: yesDermatologica Sinica, 2016
In particular pemphigus cases, the phenotypic transition between pemphigus vulgaris and pemphigus foliaceus is observed with the change of antibody profile between anti-desmoglein (Dsg) 3 antibodies and anti-Dsg1 antibodies.
Seiko Mitsui   +4 more
doaj   +1 more source

The Risk of Immune‐Mediated Skin Disease Under Dipeptidyl‐Peptidase IV Inhibitor: A Global Population‐Based Study

open access: yes
International Journal of Dermatology, Volume 65, Issue 2, Page 356-358, February 2026.
Noor Mruwat   +3 more
wiley   +1 more source

Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus

open access: yesScientific Reports, 2017
Pemphigus is an autoimmune blistering skin disease caused primarily by autoantibodies against desmoglein (Dsg)1 and 3. Here, we characterized the mechanisms engaged by pemphigus IgG from patients with different clinical phenotypes and autoantibody ...
Elias Walter   +10 more
doaj   +1 more source

Tumour necrosis factor-α polymorphism as one of the complex inherited factors in pemphigus

open access: yesMediators of Inflammation, 2003
The aim of our study was to analyse a significance of tumour necrosis factor (TNF)-α promoter gene polymorphisms in relation to the HLA-DR locus in genetic predisposition to pemphigus.
Jolanta Dorota Torzecka   +6 more
doaj   +1 more source

Monoterapia rytuksymabem w pęcherzycy liściastej

open access: yesPrzegląd Dermatologiczny, 2011
Introduction. Rituximab is a chimeric human-mouse monoclonal antibody,which binds to the CD20 antigen on B and pre-B lymphocytesand causes depletion of CD20+ cells in the mechanism of complement-dependent and independent cytolysis, antibody-dependent ...
Małgorzata Olszewska   +4 more
doaj  

The Relationship Between Blood Groups and Rh with Incidence of Pemphigus Vulgaris

open access: yesپزشکی بالینی ابن سینا, 1996
One hundred patients were studied and 93 of them suffered from Pemphigus Vulgaris and 7 of them were suffered from Pemphigus Foliaceus. The results were compared with control group.
Farhad Malekzad   +2 more
doaj  

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