Results 81 to 90 of about 12,164 (196)

Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus

open access: yesScientific Reports, 2017
Pemphigus is an autoimmune blistering skin disease caused primarily by autoantibodies against desmoglein (Dsg)1 and 3. Here, we characterized the mechanisms engaged by pemphigus IgG from patients with different clinical phenotypes and autoantibody ...
Elias Walter   +10 more
doaj   +1 more source

A Subset of Pemphigus Foliaceus Patients Exhibits Pathogenic Autoantibodies Against Both Desmoglein-1 and Desmoglein-3 [PDF]

open access: yes, 2002
In pemphigus vulgaris the major pathogenic antibody binds desmoglein-3, and mediates mucosal disease. Development of cutaneous disease is associated with acquisition of antibodies to desmoglein-1.
Lin, Mong-Shang   +11 more
core   +1 more source

Tumour necrosis factor-α polymorphism as one of the complex inherited factors in pemphigus

open access: yesMediators of Inflammation, 2003
The aim of our study was to analyse a significance of tumour necrosis factor (TNF)-α promoter gene polymorphisms in relation to the HLA-DR locus in genetic predisposition to pemphigus.
Jolanta Dorota Torzecka   +6 more
doaj   +1 more source

Monoterapia rytuksymabem w pęcherzycy liściastej

open access: yesPrzegląd Dermatologiczny, 2011
Introduction. Rituximab is a chimeric human-mouse monoclonal antibody,which binds to the CD20 antigen on B and pre-B lymphocytesand causes depletion of CD20+ cells in the mechanism of complement-dependent and independent cytolysis, antibody-dependent ...
Małgorzata Olszewska   +4 more
doaj  

Mycophenolate mofetil and enteric-coated mycophenolate sodium in the treatment of pemphigus vulgaris and pemphigus foliaceus.

open access: yes, 2014
What is known and objective: Pemphigus is a severe, potentially life-threatening autoimmune blistering disease. The use of corticosteroids has dramatically improved the prognosis and changed its course.
Spyridoula Doukaki   +7 more
core   +1 more source

The Relationship Between Blood Groups and Rh with Incidence of Pemphigus Vulgaris

open access: yesپزشکی بالینی ابن سینا, 1996
One hundred patients were studied and 93 of them suffered from Pemphigus Vulgaris and 7 of them were suffered from Pemphigus Foliaceus. The results were compared with control group.
Farhad Malekzad   +2 more
doaj  

Pemphigus foliaceus as a differential diagnosis in vesicobullous lesions

open access: yes, 2017
Given the challenge of clinical diagnosis of bullous skin lesions, this report aimed to discuss the histological changes, the presentation and clinical reasoning for diagnosis of these lesions.
Ivan Aprahamian   +3 more
core   +1 more source

Serum lipids of pemphigus foliaceus patients on long-term glucocorticoid therapy

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2003
Endemic pemphigus foliaceus, and long-term corticotherapy may affect serum lipid levels. The aim of this study was to compare serum lipids of pemphigus foliaceus patients on glucocorticoid therapy to a healthy control group.
Selma Freire de Carvalho da Cunha   +6 more
doaj  

Safety and Efficacy of Pemphigus Treatments: A Subtype-Specific Review of Conventional and Emerging Therapies

open access: yesBioChem
Background/Objectives: Pemphigus is a rare blistering disease characterized by a chronic course, associated with significant mortality and morbidity. This review article aims to delve into three Pemphigus subtypes: Pemphigus Vulgaris, Pemphigus Foliaceus
Pokphazz Christjaroon   +2 more
doaj   +1 more source

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