Results 31 to 40 of about 11,158 (184)
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +19 more
core +2 more sources
Serological Biomarkers and Their Detection in Autoimmune Bullous Skin Diseases
Autoimmune bullous diseases (AIBDs) are a group of skin-related disorders that involve damage to structures maintaining cell-cell adhesion, such as desmosomes and hemidesmosomes.
Ilana Heckler +3 more
doaj +1 more source
Case for diagnosis Caso para diagnóstico
We report a clinical case of a rare variant of pemphigus - pemphigus herpetiformis - which combines the clinical features of dermatitis herpetiformis with the immunological findings of pemphigus.
Iolanda Conde Fernandes +3 more
doaj +1 more source
IgG/IgA-pemphigus — extremely rare blistering autoimmune diseases
Purpose. To present a clinical case of IgG/IgA pemphigus in a 32-year-old woman. Material and methods. Clinical and laboratory examinations were performed to diagnose the disease: cytological examination of an impression smear from the bottom of the ...
Arfenya E. Karamova +4 more
doaj +1 more source
Autoimmune bullous skin diseases (AIBDs), such as bullous pemphigoid (BP) and pemphigus, are characterized and caused by autoantibodies targeting structural proteins.
Ulrike Raap +3 more
doaj +1 more source
A female patient aged 68 has developed polycyclically shaped erythematous plaques with herpetiform vesicles, bullae, and crusts, intensively itching. Histologic analysis has revealed bullae with acantholytic cells and eosinophils. Eosinophils were present in the epidermis as well as in the derma.
N, Mutevelić-Arslanagić +3 more
openaire +3 more sources
Pemphigus herpetiformis: analysis of the autoantibody profile during the disease course with changes in the clinical phenotype [PDF]
Pemphigus herpetiformis (PH) is a rare dapsone-responsive variant of pemphigus, characterized by annular and vesiculopustular cutaneous lesions. Most PH serum samples contain autoantibodies against desmoglein (Dsg)1, but not Dsg3, and the presence of the
Lebeau, Stéphanie +4 more
core +1 more source
Background and Objectives: Autoimmune bullous diseases (AIBDs) may be treated with intravenous immunoglobulin (IVIG) infusions. This study aimed to evaluate the benefits and safety profiles of high-dose IVIG therapy in AIBD patients, as determined by ...
Maciej Marek Spałek +2 more
doaj +1 more source
Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion. [PDF]
Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1-4 and desmocollin (Dsc) 1-3 build the adhesive core of ...
Bettina Kempf +17 more
core +2 more sources
Atypical pemphigus: autoimmunity against desmocollins and other non-desmoglein autoantigens [PDF]
In this review, we recap current knowledge about non-desmoglein autoantigens in atypical forms of autoimmune pemphigus. More than 50 keratinocyte proteins, including adhesion molecules, receptors and enzymes as well as mitochondrial proteins can be ...
Marzano, Angelo V +2 more
core +1 more source

