Results 51 to 60 of about 2,238 (218)

HSP90: A potential drug target in inflammatory skin diseases

JEADV Clinical Practice, Volume 2, Issue 3, Page 450-455, September 2023., 2023
Abstract Heat shock protein 90 (HSP90) is a chaperone protein belonging to the HSP family. HSP90 modulates clients by stabilising, folding, maturing, and tagging clients for proteasomal degradation. Several clients of HSP90 are involved in cancer development and HSP90 is required for some oncoproteins, making HSP90 a potential target in anticancer ...
A. H. Rittig, A. Bregnhøj, C. Johansen, L. Iversen   +3 more
wiley   +1 more source

Morphological spectrum of vesiculobullous skin lesions: An institutional perspective [PDF]

, 2021
Introduction: A vesiculobullous lesion of the skin encompasses a group of dermatological disorders with protean clinicopathological features. They usually occur as a part of the spectrum of various infectious, inflammatory, drug-induced, genetic, and ...
Ali, Javaria, Ali, Syed Munqaad, Aslam, Anum, Hashmi, Atif A, Irfan, Muhammad, Islam, Sabeeh, Khan, Qurat Ul Ain, Malik, Umair Arshad, Naqvi, Hanna, Yaqeen, Syed Rafay   +9 more
core   +2 more sources

Pruritus Is Associated with an Increased Risk for the Diagnosis of Autoimmune Skin Blistering Diseases: A Propensity-Matched Global Study

Biomolecules, 2023
Autoimmune bullous skin diseases (AIBDs), such as bullous pemphigoid (BP) and pemphigus, are characterized and caused by autoantibodies targeting structural proteins.
Ulrike Raap, Maren M. Limberg, Khalaf Kridin, Ralf J. Ludwig   +3 more
doaj   +1 more source

Direct and indirect immunofluorescence [PDF]

, 2010
A imunofluorescência é um valioso instrumento auxiliar no diagnóstico das dermatoses bolhosas autoimunes e desordens inflamatórias, uma vez que seus achados clínicos e histopatológicos podem não ser determinantes.
AOKI, Valéria, FREITAS, Elder L., FUKUMORI, Lígia M. I., OLIVEIRA, Zilda N. P., PÉRIGO, Alexandre M., SOUSA JR, Joaquim X.   +5 more
core   +2 more sources

Direct immunofluorescence microscopy [PDF]

, 2022
Direct immunofluorescence plays an important role in the diagnosis of autoimmune blistering diseases. The purpose of direct immunofluorescence microscopy is to detect in vivo antibodies in patient's skin or mucosa.
Diercks, Gilles F.H., Pas, Hendri H.
core   +1 more source

Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report

Indian Journal of Pathology and Microbiology, 2023
Pemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp.
Rawat Kavita, Azad Sheenam, Bahal Neelima, Bisht S Jitender   +3 more
doaj   +1 more source

IgG/IgA-pemphigus — extremely rare blistering autoimmune diseases

Vestnik Dermatologii i Venerologii, 2020
Purpose. To present a clinical case of IgG/IgA pemphigus in a 32-year-old woman. Material and methods. Clinical and laboratory examinations were performed to diagnose the disease: cytological examination of an impression smear from the bottom of the ...
Arfenya E. Karamova, Lyudmila F. Znamenskaya, Vadim V. Chikin, Viktoria A. Mihina, Maria A. Nefedova   +4 more
doaj   +1 more source

Intravenous Immunoglobulin for Autoimmune Bullous Diseases: A Case Series from a Central European Referral Center

Medicina, 2023
Background and Objectives: Autoimmune bullous diseases (AIBDs) may be treated with intravenous immunoglobulin (IVIG) infusions. This study aimed to evaluate the benefits and safety profiles of high-dose IVIG therapy in AIBD patients, as determined by ...
Maciej Marek Spałek, Monika Bowszyc-Dmochowska, Marian Dmochowski   +2 more
doaj   +1 more source

Educational Case: Bullous pemphigoid. [PDF]

Acad Pathol
The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology.
Saal RC, Roberts AA, Conran RM.
europepmc   +3 more sources

Outcomes of a fledgling public dermatology clinic in rural Australia. [PDF]

Australas J Dermatol
Abstract There is paucity of research available regarding the epidemiological characteristics of patients attending dermatology outpatient services in rural Australia. We performed a retrospective cohort study of patients attending a public dermatology clinic established at Dubbo Base Hospital in rural New South Wales. The broad range of dermatological
Li GX, Wong XL, Sebaratnam DF.
europepmc   +2 more sources