Results 81 to 90 of about 165,634 (303)

Characterization of Desmoglein-3 Epitope Region Peptides as Synthetic Antigens: Analysis of their in vitro T-cell Stimulating Efficacy, Cytotoxicity, Stability and their Conformational Features [PDF]

, 2015
Desmoglein-3 (Dsg3) adhesion protein is the main target of autoantibodies and autoreactive T cells in Pemphigus vulgaris (PV) autoimmune skin disorder.
Ahmed, Ahmed, Amagai, Amagai, Amber, Anhalt, Berkower, Carmicle, Chou, Delva, Dworschak, Enyedi, Estaquier, Ferrante, Green, Gómara, Hashimoto, Hertl, Holly, Hollósi, Jurcevic, Lin, Mahoney, Manning, Meager, Moesta, Mosmann, Partidos, Povey, Rammensee, Riechers, Ruocco, Sathyanarayana, Scharf, Scharf, Schiltz, Shanmugam, Siddiqui, Siligardi, Slater, Stanley, Sz, Szabados, Thomason, Toniolo, Vass, Veldman, Watts, Wheeler, Woody, Woody, Wucherpfennig, Wucherpfennig, Yang   +53 more
core   +1 more source

Lesions of pemphigus vulgaris on irradiated skin [PDF]

, 2009
Summary Pemphigus vulgaris (PV) is an autoimmune blistering disease produced by IgG autoantibodies against desmoglein (Dsg)3. Lesions on the skin and mucosa can, in rare cases, be induced by radiotherapy.
Aguado, L. (Leyre), España, A. (Agustín), Marquina, M. (Miren), Pretel, M. (Maider), Ruiz-Carrillo, G. (G.)   +4 more
core   +1 more source

Do serum prolactin levels correlate with antibodies against desmoglein in pemphigus vulgaris?

Advanced Biomedical Research, 2016
Background: Pemphigus vulgaris is a chronic inflammatory disease of skin, the etiology of which is not completely known. Despite the latter, anti-desmoglein antibodies play a proven role in the pathogenesis.
Fariba Iraji, Nabet Tajmirriahi, Iman Momeni, Kioumars Jamshidi, Fazlollah Hashemzehi, Amir Hossein Siadat, Alireza Asemi Esfahani   +6 more
doaj   +1 more source

Dupilumab Treatment in Pemphigus: A Report of Three Cases and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Pemphigus vulgaris (PV) and foliaceus (PF) are rare autoimmune blistering diseases traditionally treated with systemic corticosteroids, immunosuppressants, intravenous immunoglobulins, and rituximab. Nonetheless, a subset of patients remains refractory or has contraindications to these conventional therapies.
José Javier Mateos Rico, Marta Gutiérrez Pascual, María Dolores Caro Gutiérrez, Cristina Marcos Rodríguez, Javier de Quadros Malagón, Francisco Javier Vicente Martín   +5 more
wiley   +1 more source

The mapping of linear B-cell epitope regions in desmoglein 1 and 3 proteins : Recognition of immobilized peptides by pemphigus patients’ serum autoantibodies [PDF]

, 2013
Desmosomal transmembrane glycoproteins desmoglein 1and desmoglein 3 are targets of life-threatening autoimmune blistering disorders such as Pemphigus vulgaris (PV) and Pemphigus foliaceus(PF).
Bősze, Szilvia, Hudecz, Ferenc, Kárpáti, Sarolta, Silló, Pálma, Szabados, Hajnalka, Uray, Katalin   +5 more
core   +1 more source

A case report on generalized pemphigus vulgaris treated with rituximaba

Journal of Ideas in Health, 2023
Background: Pemphigus vulgaris has an obscure etiology; the presence of autoantibodies is coherent with an autoimmune disease. Rituximab a monoclonal antibody that specifically targets the CD20 antigen of B lymphocytes, has arisen as a novel treatment ...
Sakhiya Jagdish , Dhruv Jagdish Sakhiya , Jashmine Mukeshbhai Gandhi, Feral Ravi Daruwala   +3 more
doaj   +1 more source

Pemphigus vulgaris and pemphigus foliaceus: an overview of the clinical presentation, investigations and management

Clincal and Experimental Dermatology, 2019
Pemphigus diseases are cutaneous and mucous membrane blistering diseases, related to the key antigens of desmoglein 1 and 3. This article reviews the topic, including diagnosis, and provides the physician with guidance on the treatment of these difficult
V. Melchionda, K. Harman
semanticscholar   +1 more source

Direct and indirect immunofluorescence [PDF]

, 2010
A imunofluorescência é um valioso instrumento auxiliar no diagnóstico das dermatoses bolhosas autoimunes e desordens inflamatórias, uma vez que seus achados clínicos e histopatológicos podem não ser determinantes.
AOKI, Valéria, FREITAS, Elder L., FUKUMORI, Lígia M. I., OLIVEIRA, Zilda N. P., PÉRIGO, Alexandre M., SOUSA JR, Joaquim X.   +5 more
core   +2 more sources

Bispecific Dual‐Immune Checkpoint Inhibitor Associated Cutaneous Toxicity: A Report of Lorigerlimab Adverse Skin Reaction in Two Cancer Patients

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Lorigerlimab is a dual bispecific antibody (BsAb) targeting cytotoxic T‐lymphocyte‐associated protein 4 and programmed cell death protein 1 that is used for treatment of advanced solid cancers such as metastatic castration‐resistant prostate carcinoma.
Niloofar Sina, Fiorinda Muhaj, Volha Lenskaya, Doina Ivan, Victor G. Prieto, Jonathan L. Curry   +5 more
wiley   +1 more source

Pemphigus vegetans with isolated involvement of the nose and chest: rare variant of pemphigus vulgaris [PDF]

Anais Brasileiros de Dermatologia, 2019
: Pemphigus vulgaris is chronic bullous disease that manifests as bullae and erosions of skin and mucosas, with intraepidermal suprabasal cleft formation seen in the histological examination.
Raisa Ilena Caranhas Feitoza, Mônica Santos, Maria da Conceição Almeida Schettini, Silvana de Albuquerque Damasceno Ferreira   +3 more
doaj   +2 more sources