Results 51 to 60 of about 4,549 (130)

Design study for a compact laser-driven source for medical x-ray fluorescence imaging

Physical Review Accelerators and Beams, 2020
Thomson scattering sources with their hard x-ray pencil beams represent a promising candidate to drive high-resolution X-ray Fluorescence Imaging (XFI).
Theresa Brümmer, Alexander Debus, Richard Pausch, Jens Osterhoff, Florian Grüner   +4 more
doaj   +1 more source

Proton arc therapy reduces the dose delivered to circulating blood compared to intensity‐modulated proton therapy for head‐and‐neck cancer

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Background Compared to intensity‐modulated proton therapy (IMPT), proton arc therapy (PAT) has various dosimetric advantages. However, questions have been raised over whether the larger low‐dose bath during PAT may increase radiation‐induced lymphocyte killing, which is correlated with adverse clinical outcomes.
Sebastian Tattenberg, Peilin Liu, Xiaoda Cong, Cornelia Hoehr, Xuanfeng Ding   +4 more
wiley   +1 more source

High frequency percussive ventilation for respiratory immobilization in radiotherapy

Technical Innovations & Patient Support in Radiation Oncology, 2019
High frequency percussive ventilation (HFPV) employs high frequency low tidal volumes (100–400 bursts/min) to provide respiration in awake patients while simultaneously reducing respiratory motion.
Ina M. Sala, Girish B. Nair, Beverly Maurer, Thomas M. Guerrero   +3 more
doaj   +1 more source

Vision and implementation for the first U.S. carbon ion therapy center part I: Clinical rationale and the need for CIRT in the United States

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Carbon ion radiotherapy (CIRT) has evolved into an established clinical modality over the past three decades. Owing to its unique physical and biological characteristics, CIRT has demonstrated favorable outcomes for selected malignancies characterized by radioresistance, proximity to critical organs, locally advanced disease requiring safe ...
Xiaoying Liang, Chris J Beltran
wiley   +1 more source

Proton beam therapy delivered using pencil beam scanning vs. passive scattering/uniform scanning for localized prostate cancer: Comparative toxicity analysis of PCG 001-09

Clinical and Translational Radiation Oncology, 2019
Background and purpose: Patient-level benefits of proton beam therapy (PBT) relative to photon therapy for prostate cancer (PC) continue to be the focus of debate. Although trials comparing the two modalities are underway, most are being conducted using “
Mark V. Mishra, Rahul Khairnar, Søren M. Bentzen, Gary Larson, Henry Tsai, Christopher Sinesi, Carlos Vargas, George Laramore, Carl Rossi, Lane Rosen, Mingyao Zhu, William Hartsell   +11 more
doaj   +1 more source

Arms positioning in post-mastectomy proton radiation: Feasibility and development of a new arms down contouring atlas

Physics and Imaging in Radiation Oncology, 2020
Background and purpose: Breast cancer patients receiving radiation are traditionally positioned with both arms up, but this may not be feasible or comfortable for all patients.
Nicolas Depauw, Estelle Batin, Andrew Johnson, Shannon M. MacDonald, Rachel B. Jimenez   +4 more
doaj   +1 more source

Impact of robust optimization and beam configuration on the distribution stability of LET under delivery uncertainties in carbon‐ion therapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Background Carbon‐ion radiotherapy exploits high linear energy transfer (LET) to enhance biological effectiveness, and low dose‐averaged LET (LETd) within the target volume is associated with local recurrence in pancreatic cancer. Although robust optimization is widely used to improve dose robustness against delivery uncertainties, systematic ...
Wisawa Phongprapun, Mutsumi Tashiro
wiley   +1 more source

DoseRAD2026: A benchmark dataset for AI‐accelerated photon and proton dose calculation in radiotherapy

Medical Physics, Volume 53, Issue 11, November 2026.
Abstract Purpose Accurate dose calculation is a fundamental component of modern radiotherapy, enabling precise tumor irradiation while sparing surrounding healthy tissue. With the increasing adoption of magnetic resonance imaging (MRI)‐guided radiotherapy and growing interest in real‐time adaptive radiotherapy, there is a demand for fast and accurate ...
Fan Xiao, Nikolaos Delopoulos, Niklas Wahl, Lennart Volz, Lina Bucher, Matteo Maspero, Miguel Palacios, Muheng Li, Samir Schulz, Viktor Rogowski, Ye Zhang, Zoltan Perko, Christopher Kurz, George Dedes, Guillaume Landry, Adrian Thummerer   +15 more
wiley   +1 more source

Spot size reduction and minibeam creation in a proton PBS nozzle using multipole permanent magnets

Medical Physics, Volume 53, Issue 11, November 2026.
Abstract Background Smaller spot sizes in pencil beam scanning (PBS) nozzles are generally desired to allow more conformal treatments and to spare normal tissue and organs at risk. The production of small diameter proton beams, especially proton minibeams, is challenging because long drift spaces in standard PBS nozzles exacerbate effects of MCS and ...
Grant A. McAuley
wiley   +1 more source

Local Radiation Complications Following Proton Therapy for Uveal Melanoma

Oftalʹmologiâ
Purpose: to study the frequency and clinical symptoms of local radiation complications that occur after proton therapy in patients with uveal melanoma using pencil beam scanning technology.
I. E. Panova, E. M. Svistunova, N. A. Vorobyev, N. I. Martynova, I. A.I. Al-Mousa   +4 more
doaj   +1 more source