Synthesis of new sulfonylamido-penicillanic acid sulfones inhibitors of .BETA.-lactamases.
The Journal of Antibiotics, 1994 Three new sulfonylamido-penicillanic acid sulfones have been prepared by reaction of 6-aminopenicillanic esters with the monoester or monoamide derivatives obtained in nucleophilic substitution reactions by alcohol or aniline on the carboxyl chloride function of sulfoacetic dichloride followed by oxidation.
S, Vanwetswinkel +2 more
openaire +3 more sources
Novel Penicillin-Type Analogues Bearing a Variable Substituted 2-Azetidinone Ring at Position 6: Synthesis and Biological Evaluation [PDF]
, 2015 The synthesis and the biological activity of novel semi-synthetic β-lactam compounds containing an azetidinone moiety joined to the amino-nitrogen of the (+)-6-aminopenicillanic acid (6-APA) as new antibacterial agents is reported.
De Rosa Margherita +4 more
core +1 more source
Piperacillin/Tazobactam (ZOSYN)
, 1996 Infectious Diseases in Obstetrics and Gynecology, Volume 4, Issue 5, Page 258-262, 1996.
Stephanie M. Culver, Mark G. Martens
wiley +1 more source
Synthesis and biological evaluation of new Mannich and Schiff bases containing 1,2,4-triazole and 1,3,4-oxadiazole nucleus [PDF]
, 2016 5-(Pyridine-3-yl)-1, 3, 4-oxadiazole-2-thiole 2, obtaining starting from nicotinic acid hydrazide were converted to the corresponding Mannich bases (3a–c) by the reaction with several heterocyclic amines in the presence of formaldehyde. 1,2,4-Triazole-
Ceylan, Şule
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Interventions to improve antibiotic prescribing practices for hospital inpatients [PDF]
, 2017 Background Antibiotic resistance is a major public health problem. Infections caused by multidrug-resistant bacteria are associated with prolonged hospital stay and death compared with infections caused by susceptible bacteria. Appropriate antibiotic use
Brown, Erwin +8 more
core +3 more sources
Pirbenicillin, a New Semisynthetic Penicillin with Broad-Spectrum Activity [PDF]
, 1976 Pirbenicillin is a new semisynthetic penicillin which inhibited 67% of isolates of Proteus aeruginosa tested in our laboratory, 93% of P. mirabilis , 31% of Enterobacter
Gerald P. Bodey +2 more
core +1 more source
Analysis of the physical interactions of HMGB1 by the two-hybrid system [PDF]
, 2016 Traballo fin de grao (UDC.CIE). Bioloxía. Curso 2015/2016[Resumen] El cáncer de próstata es el segundo cáncer más diagnosticado en los hombres a nivel mundial, siendo el primero tanto en Europa como en España.
Feijóo Buján, Ana
core
1-Oxo-6-(2-phenylacetylamino)-1-penicillanic acid
Acta Crystallographica Section E Structure Reports Online, 2006 The crystal structure of the title compound (CAS: 4052–54-4), C16H18N2O5S, contains O—H⋯O and N—H⋯O hydrogen bonds. The four-membered ring is folded and the five-membered ring has an envelope conformation.
Er-Hong Duan +3 more
openaire +1 more source
Kinetic perspectives for the degradation of oxacillin: A penicillanic acid derivative
Edelweiss Applied Science and TechnologyOxidation of oxacillin, a penicillanic acid derivative, has been predicted by monoperiodatocuprate [MPC (III)] at 25°C with 0.10 mol dm-3 ionic strength, in an aqueous alkaline medium by UV/Visible spectrophotometric analysis, for which 1:4 stoichiometry of oxacillin: MPC (III) is visible.
Yuv Raj Sahu +2 more
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Preparation of Chiral Oxoazetidinesulfinates [PDF]
, 1989 Diastereomeric oxoazetidinesulfinates IV were prepared from penicillanate S,S-dioxide (Sulbactam) via sulfinic acid I and sulfinyl chlorides II. Both epimers IVa and IVb gave the same oxoazetidinesulfonate V upon oxidation.
Branimir Gašpert +2 more
core +1 more source