Results 31 to 40 of about 4,314 (176)

High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers [PDF]

, 1985
In plasma and urine of 10 healthy volunteers after intravenous administration of 4 g mezlocillin and piperacillin, respectively, the parent compounds as well as degradation products were assayed by high-performance liquid chromatography. Ioxitalamic acid,
Bartoschik-Wich, B., Grobecker, H., Kees, Frieder K., Meyer, G. P., Naber, K. G., Stockmann, P.   +5 more
core  

Anthraquinone Sulfonates as Water‐Soluble Photocatalysts: Synthetic Applications and Perspectives

ChemPhotoChem, Volume 9, Issue 8, August 2025.
The development of photochemistry in water is rapidly advancing, and the demand for water‐soluble photocatalysts is increasing. Accordingly, anthraquinone sulfonates are interesting options for the activation of organic molecules through H‐atom transfer, proton‐coupled electron transfer, or the generation of reactive oxygen species.
Daniel Kolb, Andrey Fedulin, Burkhard König   +2 more
wiley   +1 more source

A Sensitive Spectrophotometric Determination of Ritodrine, Pentazocine, Isoxsuprine Hydrochlorides and Amoxicillin in Pure and Pharmaceutical Samples

Journal of Chemistry, Volume 5, Issue 1, Page 100-106, 2008., 2008
A simple, accurate and highly sensitive spectrophotometric method for the determination of ritodrine hydrochloride (RTH), pentazocine hydrochloride (PZH), isoxsuprine hydrochloride (ISH) and amoxicillin (AMX) is described. The method is based on the oxidation of the studied drugs by a known excess of chloramine – T (CAT) in hydrochloric acid medium and
H. D. Revanasiddappa, M. A. Veena
wiley   +1 more source

Pharmacokinetics-pharmacodynamics of tazobactam in combination with cefepime in an in vitro infection model [PDF]

, 2017
We previously demonstrated that for tazobactam administered in combination with ceftolozane, the pharmacokinetic-pharmacodynamic (PK-PD) index that best described tazobactam efficacy was the percentage of the dosing interval that tazobactam ...
Ambrose, Paul G., Bhavnani, Sujata M., Conde, Haley, Livermore, David M., McCauley, Jennifer, Rubino, Christopher M., Tenero, David, Turner, Simon, VanScoy, Brian D.   +8 more
core   +1 more source

A review of antibiotic safety in pregnancy—2025 update

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 4, Page 227-237, April 2025.
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Johny Nguyen, Victoria Madonia, Christopher M. Bland, Kayla R. Stover, Lea S. Eiland, Julia Keating, Madeline Lemmon, P. Brandon Bookstaver, as part of the Southeastern Research Group Endeavor (SERGE‐45) research network   +8 more
wiley   +1 more source

Study of the Comparative Activity of Piperacillin/Tazobactam with Currently Available Antibiotics against 8206 Aerobic Isolates

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 8, Issue 3, Page 147-153, 1997., 1996
OBJECTIVES: To compare the activity of piperacillin‐tazobactam with piperacillin and other parenterally administered antibiotics against aerobic Gram‐negative bacilli and Gram‐positive cocci isolated from across Canada, and to determine the prevalence of resistance mediated by extended‐spectrum cephalosporinases.
Kevin R Forward, Donald E Low, Michel Laverdiere, Robert Rennie, Andrew E Simor, Patricia A Franks, Members of the Canadian Piperacillin/Tazobactam Study Group   +6 more
wiley   +1 more source

Effect of pO2 and pH on synergy of tazobactam and β-lactam antibiotics against β-lactamase producing Enterobacteriaceae [PDF]

, 2017
Synergy between tazobactam and ceftriaxone or piperacillin against β-lactamase producing Enterobacteriaceae was not influenced by the presence or absence of oxygen.
Blaser, Jürg, König, Christiane
core  

Selection of mutants with resistance or diminished susceptibility to ceftazidime/avibactam from ESBL- and AmpC- producing Enterobacteriaceae [PDF]

, 2018
Introduction: Difficult Gram-negative infections are increasingly treated with new β-lactamase inhibitor combinations, e.g. ceftazidime/avibactam.
Doumith, Michel, Jamrozy, Dorota, Livermore, David M., Mushtaq, Shazad, Nichols, Wright W., Woodford, Neil   +5 more
core   +1 more source

Sulbactam–Durlobactam: A Novel Antibiotic Combination for the Treatment of Acinetobacter baumannii–Calcoaceticus Complex (ABC) Hospital‐Acquired Bacterial Pneumonia and Ventilator‐Associated Bacterial Pneumonia

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Purpose: To evaluate the pharmacology, pharmacokinetics, pharmacodynamics, antimicrobial activity, efficacy, safety, and the regulatory status of sulbactam–durlobactam. Summary: Sulbactam–durlobactam is a recently approved antimicrobial combination of two β‐lactamase inhibitors for the treatment of hospital‐acquired bacterial pneumonia (HABP) and ...
Wissam K. Kabbara, Elina Sadek, Hanine Mansour, Vijay Gondil   +3 more
wiley   +1 more source

Dental Biopolymer Composites with Antibiotics, Bisphosphonate, and Hydroxyapatite for Possible Use in Bone Tissue Regeneration

Journal of Chemistry, Volume 2024, Issue 1, 2024.
The aim of the present study was to formulate new variants of synthetic and animal‐source bone materials coated with different biopolymers, containing antibiotics (ampicillin and oxacillin) and alendronate drugs. Validation consists in establishing mixtures that do not present interactions between components.
Mihaela Maria Budiul, Gabriela Vlase, Daniel Negru, Dorinel Okolišan, Ionela-Amalia Bradu, Alexandra Tăşală, Alexandru Pahomi, Titus Vlase, Daniela Jumanca, Atena Galuscan, Paula Sfirloaga, Nicoleta Carabă, Roxana Popescu, Anamaria Matichescu, Ajaya Kumar Singh   +14 more
wiley   +1 more source