Results 21 to 30 of about 4,314 (176)
Structural and Functional Aspects of Class A Carbapenemases. [PDF]
, 2016 The fight against infectious diseases is probably one of the greatest public health challenges faced by our society, especially with the emergence of carbapenem-resistant gram-negatives that are in some cases pan-drug resistant.
Dortet, L, Iorga, BI, Naas, T
core +3 more sources
Optimal control of enzymatic hydrolysis of lignocellulosic biomass [PDF]
, 2016 Cellulose hydrolysis is a key step in lignocellulosic ethanol production. At present, commercial production of lignocellulosic ethanol is limited due to the long hydrolysis times and requirement of large quantity of expensive enzymes.
Fenila, F., Yogendra Shastri
core +2 more sources
Functional expression of a penicillin acylase from the extreme thermophile Thermus thermophilus HB27 in Escherichia coli [PDF]
, 2012 Background: Penicillin acylases (PACs) are enzymes of industrial relevance in the manufacture of beta-lactam antibiotics. Development of a PAC with a longer half-life under the reaction conditions used is essential for the improvement of the operational ...
Berenguer, José +4 more
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Journal of Analytical Methods in Chemistry, Volume 2014, Issue 1, 2014., 2014 Six Sigma methodology has been successfully applied to daily operations by several leading global private firms including GE and Motorola, to leverage their net profits. Comparatively, limited studies have been conducted to find out whether this highly successful methodology can be applied to research and development (R&D).
Anirban Nandi +5 more
wiley +1 more source
«A Chain is gonna come». Building a penicillin production plant in post-war Italy [PDF]
, 2011 In 1947, Ernst Chain moved from Oxford to Rome, hired as head of a new biochemistry department and of a penicillin production pilot plant in the Istituto Superiore di Sanità (Higher Health Institute).
Capocci, Mauro
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Enzymatic Synthesis of Ampicillin: Nonlinear Modeling, Kinetics Estimation, and Adaptive Control
BioMed Research International, Volume 2012, Issue 1, 2012., 2012 Nowadays, the use of advanced control strategies in biotechnology is quite low. A main reason is the lack of quality of the data, and the fact that more sophisticated control strategies must be based on a model of the dynamics of bioprocesses. The nonlinearity of the bioprocesses and the absence of cheap and reliable instrumentation require an enhanced
Monica Roman, Dan Selişteanu, T. Akutsu
wiley +1 more source
Activity of ceftolozane/tazobactam against surveillance and ‘problem’ Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles [PDF]
, 2017 Background: We assessed the activity of ceftolozane/tazobactam against consecutive isolates collected in the BSAC Bacteraemia Surveillance from 2011 to 2015 and against ‘problem’ isolates sent to the UK national reference laboratory from July 2015, when ...
Aiysha Chaudhry +43 more
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Occupational Asthma in Antibiotic Manufacturing Workers: Case Reports and Systematic Review
Journal of Allergy, Volume 2011, Issue 1, 2011., 2011 Background. The risks of occupational asthma (OA) from antibiotics are uncertain. We report 4 new cases and a systematic review of the literature. Methods. Cases were identified through a specialist clinic, each underwent specific provocation testing (SPT). We subsequently reviewed the published literature. Results.
Sara Díaz Angulo +5 more
wiley +1 more source
Post Penicillin Antibiotics: From acceptance to resistance? [PDF]
, 2000 Edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, in London, on 12 May 1998. First published by the Wellcome Trust, 2000. ©The Trustee of the Wellcome Trust, London, 2000.
Reynolds, LA, Tansey, EM
core
The Kinetics of Ampicillin Release from Hydroxyapatite for Bones Regeneration
International Journal of Chemical Engineering, Volume 2009, Issue 1, 2009., 2009 Semisynthetic beta‐lactam antibiotics are among the most used pharmaceuticals. Their use in veterinary and human medicine is in continuous expansion. There is a growing need for developing bioactive implants. Advantages of implantable drug delivery tools can include high release efficiency, precise dose control, low toxicity, and allow to overcome ...
Giovanilton Ferreira da Silva +5 more
wiley +1 more source