Results 121 to 130 of about 804,907 (316)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

H+ISFET-based biosensor for determination of penicillin G

open access: yes, 1998
A biosensor based on an H+ ion sensitive field effect transistor (H+-ISFET) and penicillin G acylase has been developed. The response time of the sensor to different concentrations of penicillin G was 30 s.
Liu JG   +5 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Penicillin Resistance Compromises Nod1-Dependent Proinflammatory Activity and Virulence Fitness of Neisseria meningitidis

open access: yes, 2013
SummaryNeisseria meningitidis is a life-threatening human bacterial pathogen responsible for pneumonia, sepsis, and meningitis. Meningococcal strains with reduced susceptibility to penicillin G (PenI) carry a mutated penicillin-binding protein (PBP2 ...
LeBourhis, Lionel   +24 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The Efficiency of Penicillin Production by P. rubens

open access: yes
This thesis discusses the efficiency of penicillin production by P. rubens and how this efficiency has improved over the years. Key aspects such as genetic engineering initiated by classical strain improvement programs as well of optimisation of ...
Moyo, Lindokuhle Zinzile
core  

Penicillin G plus an aminoglycoside in febrile neutropenia

open access: yes, 2013
Lege og forsker Dag Torfoss har i sin avhandling Penicillin G plus an aminoglycoside in febrile neutropenia oppsummert studier med penicillin og aminoglykosid ved feber etter cellegiftbehandling.
Torfoss, Dag
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Examination of penicillin use in Hungary

open access: yes
Diplomadolgozatomban bemutatom a penicillin használatának alakulását. Az antibiotikum rezisztens törzsek megjelenését, terjedését, valamint annak mértékét.
Szabó, Lévainé, Gyöngyi
core  

Pneumonia Caused by Penicillin-Nonsusceptible Streptococcus Pneumoniae: Clinical Characteristics, Prognostic Factors, and Outcomes

open access: yes, 2009
Background and purpose: Pneumococcal pneumonia caused by penicillin nonsusceptible Streptococcus pneumoniae (PNSSP) is increasing worldwide. To better understand this infection , patients with pneumococcal pneumonia treated at National Taiwan University ...
吳茲端;薛博仁;李麗娜;陸坤泰;楊泮池   +1 more
core  

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